Protein Alignment Prps and Prpsap1

DIOPT Version :9

• Sequence 1: NP_729528.2
• Gene: Prps / 39132
• FlyBaseID: FBgn0036030
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: XP_006534080.1
• Gene: Prpsap1 / 67763
• MGIID: 1915013
• Length: 390
• Species: Mus musculus
• Alignment Length: 404
• Identity: 161/404 - (39%)
• Similarity: 224/404 - (55%)
• Gaps: 67/404 - (16%)

  Fly    23 PIRARSLIRDNLEKQAGCLNLIHSRMPNIKVFSGTSH---PDLAQRIVDRLGIDLGKVVTKKFSN 84
            |:.|.|.:|....:.|.. ..:::.....:|||..|.   .:||:||.:|||.:|||.|..:.:|
Mouse    10 PLSACSALRVPRARPAAS-PAMNAARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETN 73

  Fly    85 LETCVEIGESVRGEDVYIVQSGSG-----EINDNLMELLIMINACKIASASRVTAVIPCFPYARQ 144
            .||.|||.|||||:|::|:|:...     ::|..:||||||..|.|.|.|..:..|||.|||::|
Mouse    74 GETRVEIKESVRGQDIFIIQTIPSFYCFRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQ 138

  Fly   145 DKKDKLAGSEDNAESKKLAKKNYDWKFRSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFD 209
            .                        |.|.|..|..||:|:||:.||..||||||||..:|||||.
Mouse   139 S------------------------KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFS 179

  Fly   210 IPVDNLYAEPAVLKWIKENIPEWKNSIIV--SPDAGGAKRVTSIADRLNVEFALIHKERK----- 267
            .|||||.|.|.:|::|:|.||.::|::||  ||||  |||..|.|:||.:..|:||.|.:
Mouse   180 FPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDA--AKRAQSYAERLRLGLAVIHGEAQCTELD 242

  Fly   268 -------------------------KANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRLV 307
                                     .|.|...:.:||||..:|||:|||:.|...:.|.||:.|.
Mouse   243 MDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAEILK 307

  Fly   308 EAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQDGHMRDCPKIQCIDVSMMFAEAVRR 372
            |.||.|:|.:.||||.|..|...|..:..:.||||||:|.:.....||||:.:|:|::.:||:||
Mouse   308 ERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHELQKLQCPKIKTVDISLILSEAIRR 372

  Fly   373 THNGESVSYLFSNV 386
            .|||||::|||.|:
Mouse   373 IHNGESMAYLFRNI 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prps	NP_729528.2	PrsA	48..383	CDD:223538	153/374 (41%)
Prpsap1	XP_006534080.1	Pribosyltran_N	38..160	CDD:379372	56/145 (39%)
		Pribosyl_synth	201..384	CDD:373138	71/184 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60704
OrthoDB	1	1.010	-	-		D1043963at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.830