Protein Alignment Prps and PRPSAP2

DIOPT Version :9

• Sequence 1: NP_729528.2
• Gene: Prps / 39132
• FlyBaseID: FBgn0036030
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_001340027.1
• Gene: PRPSAP2 / 5636
• HGNCID: 9467
• Length: 423
• Species: Homo sapiens
• Alignment Length: 363
• Identity: 148/363 - (40%)
• Similarity: 215/363 - (59%)
• Gaps: 55/363 - (15%)

  Fly    55 SGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLI 119
            |.:|..:|:::|.:|||:::|||...:..|.||.|:|.|||||:||:|:|:.|.::|..:|||||
Human    81 SNSSCMELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLI 145

  Fly   120 MINACKIASASRVTAVIPCFPYARQDKKDKLAGSEDNAESKKLAKKNYDWKFRSRAPISAKLVAN 184
            |:.|||.:.|..:..|||.|||::|                        .|.|.|..|.:||:|:
Human   146 MVYACKTSCAKSIIGVIPYFPYSKQ------------------------CKMRKRGSIVSKLLAS 186

  Fly   185 MLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPEWKNSIIVSPDAGGAKRVT 249
            |:..||..|:||||||..:|||||:||||||.|.|.:|::|:|.||:::|::||:.....|||..
Human   187 MMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQ 251

  Fly   250 SIADRLNVEFALIHKERKKA-------------------------------NEVASMVLVGDVKD 283
            |.|:||.:..|:||.|.:.|                               .|...:.:||||..
Human   252 SFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSVAAIHPSLEIPMLIPKEKPPITVVGDVGG 316

  Fly   284 KIAILVDDMADTCGTIVHAADRLVEAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQD 348
            :|||:|||:.|...:.:.||:.|.|.||.|::.:.|||:.|..|..||..:..:.||||||||.:
Human   317 RIAIIVDDIIDDVDSFLAAAETLKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHE 381

  Fly   349 GHMRDCPKIQCIDVSMMFAEAVRRTHNGESVSYLFSNV 386
            .....||||:.:|:||:.:||:||.|||||:||||.|:
Human   382 VQKLQCPKIKTVDISMILSEAIRRIHNGESMSYLFRNI 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prps	NP_729528.2	PrsA	48..383	CDD:223538	145/358 (41%)
PRPSAP2	NP_001340027.1	Pribosyltran_N	74..192	CDD:316325	51/134 (38%)
		Pribosyl_synth	233..417	CDD:291252	68/183 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60704
OrthoDB	1	1.010	-	-		D1043963at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.830