DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prps and prps1b

DIOPT Version :9

Sequence 1:	NP_729528.2	Gene:	Prps / 39132	FlyBaseID:	FBgn0036030	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_001070036.1	Gene:	prps1b / 560827	ZFINID:	ZDB-GENE-030131-4011	Length:	318	Species:	Danio rerio

Alignment Length:	340	Identity:	282/340 - (82%)
Similarity:	302/340 - (88%)	Gaps:	23/340 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 MPNIKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEIND 112
            |||||:|||:||.||:|:|.||||::|||||||||||.|||||||||||||||||||||.|||||
Zfish     1 MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEIND 65

  Fly   113 NLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKLAGSEDNAESKKLAKKNYDWKFRSRAPI 177
            |||||||||||||||||:|||||||||||||||||||                       |||||
Zfish    66 NLMELLIMINACKIASATRVTAVIPCFPYARQDKKDK-----------------------SRAPI 107

  Fly   178 SAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPEWKNSIIVSPDA 242
            |||||||||||:|||||||||||||||||||||||||||||||||||||||||||||..||||||
Zfish   108 SAKLVANMLSVSGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPEWKNCTIVSPDA 172

  Fly   243 GGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRLV 307
            |||||||||||||||:||||||||||||||..|||||||||::|||||||||||||:.||||:|:
Zfish   173 GGAKRVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTVCHAADKLI 237

  Fly   308 EAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQDGHMRDCPKIQCIDVSMMFAEAVRR 372
            .|||||||||||||||||||||||||||||||||||||||:..|:.|||||.||:||:.|||:||
Zfish   238 SAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEEKMKHCPKIQVIDISMILAEAIRR 302

  Fly   373 THNGESVSYLFSNVP 387
            ||||||||||||:||
Zfish   303 THNGESVSYLFSHVP 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prps	NP_729528.2	PrsA	48..383	CDD:223538	277/334 (83%)
prps1b	NP_001070036.1	PrsA	1..313	CDD:223538	277/334 (83%)
		Pribosyltran_N	4..120	CDD:290508	104/138 (75%)
		PRTases_typeI	161..313	CDD:294217	129/151 (85%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581579
Domainoid	1	1.000	205	1.000	Domainoid score	I2887
eggNOG	1	0.900	-	-		E1_COG0462
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68275
Inparanoid	1	1.050	557	1.000	Inparanoid score	I1075
OMA	1	1.010	-	-		QHG60704
OrthoDB	1	1.010	-	-		D1043963at2759
OrthoFinder	1	1.000	-	-		FOG0000593
OrthoInspector	1	1.000	-	-		otm25779
orthoMCL	1	0.900	-	-		OOG6_100356
Panther	1	1.100	-	-	O	PTHR10210
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3885
SonicParanoid	1	1.000	-	-		X462
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800