Protein Alignment Prps and prps2

DIOPT Version :9

• Sequence 1: NP_729528.2
• Gene: Prps / 39132
• FlyBaseID: FBgn0036030
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_001011074.1
• Gene: prps2 / 496485
• XenbaseID: XB-GENE-983985
• Length: 318
• Species: Xenopus tropicalis
• Alignment Length: 340
• Identity: 278/340 - (81%)
• Similarity: 300/340 - (88%)
• Gaps: 23/340 - (6%)

  Fly    48 MPNIKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEIND 112
            ||||.:|||:||.||:|::.:|||::|||||||||||.||.||||||||||||||:|||.|||||
 Frog     1 MPNIVLFSGSSHQDLSQKVAERLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEIND 65

  Fly   113 NLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKLAGSEDNAESKKLAKKNYDWKFRSRAPI 177
            ||||||||||||||||:||||||||||||||||||||                       |||||
 Frog    66 NLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDK-----------------------SRAPI 107

  Fly   178 SAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPEWKNSIIVSPDA 242
            |||||||||||||||||||||||||||||||||||||||||||||:||:||||||||||||||||
 Frog   108 SAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIPEWKNSIIVSPDA 172

  Fly   243 GGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRLV 307
            ||||||||||||||||||||||||||||||..|||||||||::||||||||||||||.||||:|:
 Frog   173 GGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLL 237

  Fly   308 EAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQDGHMRDCPKIQCIDVSMMFAEAVRR 372
            .||||||||||||||||||||||||||.||||||||||||:..|:.|.|||.||:||:.|||:||
 Frog   238 SAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKQCSKIQVIDISMILAEAIRR 302

  Fly   373 THNGESVSYLFSNVP 387
            ||||||||||||:||
 Frog   303 THNGESVSYLFSHVP 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prps	NP_729528.2	PrsA	48..383	CDD:223538	273/334 (82%)
prps2	NP_001011074.1	PrsA	1..313	CDD:223538	273/334 (82%)
		Binding of phosphoribosylpyrophosphate. /evidence=ECO:0000255	212..227		12/14 (86%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	198	1.000	Domainoid score	I3029
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	550	1.000	Inparanoid score	I1122
OMA	1	1.010	-	-		QHG60704
OrthoDB	1	1.010	-	-		D1043963at2759
OrthoFinder	1	1.000	-	-		FOG0000593
OrthoInspector	1	1.000	-	-		otm48224
Panther	1	1.100	-	-	O	PTHR10210
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3885
SonicParanoid	1	1.000	-	-		X462
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.110