Protein Alignment Prps and Prpsap2

DIOPT Version :9

• Sequence 1: NP_729528.2
• Gene: Prps / 39132
• FlyBaseID: FBgn0036030
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_001157714.1
• Gene: Prpsap2 / 212627
• MGIID: 2384838
• Length: 369
• Species: Mus musculus
• Alignment Length: 363
• Identity: 147/363 - (40%)
• Similarity: 214/363 - (58%)
• Gaps: 55/363 - (15%)

  Fly    55 SGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLI 119
            |.:|..:|:::|.:|||:::|||...:..|.||.|:|.|||||:||:|:|:.|.::|..:|||||
Mouse    27 SNSSCMELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTISKDVNTTIMELLI 91

  Fly   120 MINACKIASASRVTAVIPCFPYARQDKKDKLAGSEDNAESKKLAKKNYDWKFRSRAPISAKLVAN 184
            |:.|||.:.|..:..|||.|||::|                        .|.|.|..|.:||:|:
Mouse    92 MVYACKTSCAKSIIGVIPYFPYSKQ------------------------CKMRKRGSIVSKLLAS 132

  Fly   185 MLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPEWKNSIIVSPDAGGAKRVT 249
            |:..||..|:||||||..:|||||:||||||.|.|.:|::|:|.||:::|::||:.....|||..
Mouse   133 MMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQ 197

  Fly   250 SIADRLNVEFALIHKERKKA-------------------------------NEVASMVLVGDVKD 283
            |.|:||.:..|:||.|.:.|                               .|...:.:||||..
Mouse   198 SFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSVAAIHPSLEIPMLIPKEKPPITVVGDVGG 262

  Fly   284 KIAILVDDMADTCGTIVHAADRLVEAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQD 348
            :|||:|||:.|...:.:.||:.|.|.||.|::.:.|||:.|..|...|..:..:.||||||||.:
Mouse   263 RIAIIVDDIIDDVDSFLAAAETLKERGAYKIFVMATHGLLSSDAPRLIEESAIDEVVVTNTIPHE 327

  Fly   349 GHMRDCPKIQCIDVSMMFAEAVRRTHNGESVSYLFSNV 386
            .....||||:.:|:||:.:||:||.|||||:||||.|:
Mouse   328 IQKLQCPKIKTVDISMILSEAIRRIHNGESMSYLFRNI 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prps	NP_729528.2	PrsA	48..383	CDD:223538	144/358 (40%)
Prpsap2	NP_001157714.1	Pribosyltran_N	20..138	CDD:404648	51/134 (38%)
		Pribosyl_synth	179..363	CDD:405288	67/183 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60704
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820