Protein Alignment CG16719 and Spef1

DIOPT Version :10

• Sequence 1: NP_648344.1
• Gene: CG16719 / 39131
• FlyBaseID: FBgn0036029
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_081917.1
• Gene: Spef1 / 70997
• MGIID: 3513546
• Length: 234
• Species: Mus musculus
• Alignment Length: 273
• Identity: 54/273 - (19%)
• Similarity: 102/273 - (37%)
• Gaps: 62/273 - (22%)

  Fly   421 PMVFRNLREMFKLDAADYM------------MSICGDDGLREISSPGKSGSIFY----------L 463
            |::..|.:  |.||....:            :||....||..:.:.|::....|          :
Mouse     3 PVIAANTK--FSLDLLKQLCQKSKDNVLFSPLSISSALGLVLLGAKGETADQMYKVLQFFKETII 65

  Fly   464 SHDDRFVIKTL----KRSELKVLLRMLPRYYEHVGDYENTLITK-----FFGVHRIKLKWGKKVR 519
            .||   :.:.:    |..:||:..||   :.:...|:.:..:.|     |.|:..:..|...:..
Mouse    66 YHD---LYEAINQGGKNRKLKLYNRM---FGDRTIDFLDGYLDKCEEWCFAGIRNVDFKTNPEAA 124

  Fly   520 FVVMGNMFCTELKIHRRYD-------LKGSTQGRYTEKNKIGEKTTLKD--LDLAYEFHMDKLLR 575
            ...:......:.|:..:.|       .|.|.:      |.:|::...||  |.|....|.:....
Mouse   125 RAQINTWVKNKTKVDCKPDADQKCDPYKNSIE------NLLGKEDVSKDSVLALISVMHFEARWA 183

  Fly   576 EALFKQIILDCSFLESLQILDYSLLLGLHFRAPDPLTDILEPPNEMSDQESDSVGSVDVNLPREP 640
            :: |:.:..:....::.|::..:.:..|. ..||..:.:||.|.|.||.      |..:.||.:.
Mouse   184 QS-FEPLHTNKDKAQNGQMMQTTQIFPLG-EIPDADSKMLEIPYENSDV------SFLIILPNQN 240

  Fly   641 SIPPKGLLMVTHE 653
            ...||.|..:|||
Mouse   241 DGLPKLLDSMTHE 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16719	NP_648344.1	CH_2	9..99	CDD:461871
Spef1	NP_081917.1	CH_2	13..104	CDD:461871	16/96 (17%)
		Essential for homodimerization and microtubule bundling activity. /evidence=ECO:0000269|PubMed:30535028	181..234		12/60 (20%)