DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTub67C and TUA2

DIOPT Version :9

Sequence 1:	NP_524009.2	Gene:	alphaTub67C / 39130	FlyBaseID:	FBgn0087040	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_175423.1	Gene:	TUA2 / 841425	AraportID:	AT1G50010	Length:	450	Species:	Arabidopsis thaliana

Alignment Length:	462	Identity:	296/462 - (64%)
Similarity:	371/462 - (80%)	Gaps:	17/462 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MREVVSIQIGQCGIQIGNACWELYLLEHGINLDGSLKTKEELTASGSSASVGHDTSANDA-RTFF 64
            |||.:||.|||.|||:||||||||.|||||..||.:.         |..:||   ..:|| .|||
plant     1 MRECISIHIGQAGIQVGNACWELYCLEHGIQPDGQMP---------SDKTVG---GGDDAFNTFF 53

  Fly    65 TETGNGKQVPRSIFVDLEPTVIDDVRNGCMRELYHPEQLISGKEDAANNYARGRYSIGKEVIDRV 129
            :|||.||.|||::||||||||||:||.|..|:|:|||||||||||||||:|||.|:||||::|..
plant    54 SETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDLC 118

  Fly   130 TSRLQKIAEQCDSLQGFLIFHSLGGGTGSGFTSLLVERLSTDYSKKCKLDFAVYPSPKVSTAVVE 194
            ..|::|:|:.|..|||||:|:::|||||||..|||:||||.||.||.||.|.|||||:|||:|||
plant   119 LDRIRKLADNCTGLQGFLVFNAVGGGTGSGLGSLLLERLSVDYGKKSKLGFTVYPSPQVSTSVVE 183

  Fly   195 PYNALLTTHSTMDHSDCVFMVDNEAIYDICNNSLGVDRPAYRNLNRLIAQIVSSTTASLRFSGSM 259
            |||::|:|||.::|:|...::|||||||||..||.::||.|.|||||::|::||.||||||.|::
plant   184 PYNSVLSTHSLLEHTDVSILLDNEAIYDICRRSLSIERPTYTNLNRLVSQVISSLTASLRFDGAL 248

  Fly   260 NVDLNEFQTNLVPFPRIHFPLVAYAPLMSAERSAHEQHAITTLTNACFESSNMMVKCDPRAGKFM 324
            |||:.||||||||:|||||.|.:|||::|||::.|||.::..:||:.||.::||.|||||.||:|
plant   249 NVDVTEFQTNLVPYPRIHFMLSSYAPVISAEKAFHEQLSVAEITNSAFEPASMMAKCDPRHGKYM 313

  Fly   325 ACCMLYRGDVVPKDVNAAVSAIKSKRHIQFVDWCPTGFKIGINYEKPAFVPDGDLAKTSRACCML 389
            |||::||||||||||||||..||:||.||||||||||||.||||:.|..||.|||||..||.||:
plant   314 ACCLMYRGDVVPKDVNAAVGTIKTKRTIQFVDWCPTGFKCGINYQPPTVVPGGDLAKVQRAVCMI 378

  Fly   390 SNTTAISVAFSNLSYKFDLMFKKRAFVHWYVGEGMEEGEFTEARENIAVLERDFEEVGLDNAEEG 454
            ||:|:::..||.:.:|||||:.||||||||||||||||||:||||::|.||:|:||||    .||
plant   379 SNSTSVAEVFSRIDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVG----AEG 439

  Fly   455 GDEDFDE 461
            ||::.||
plant   440 GDDEDDE 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub67C	NP_524009.2	alpha_tubulin	2..446	CDD:276955	286/444 (64%)
TUA2	NP_175423.1	PLN00221	1..450	CDD:177802	296/462 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D514396at2759
OrthoFinder	1	1.000	-	-		FOG0000082
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100108
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.820