Protein Alignment alphaTub67C and TUBE1

DIOPT Version :9

• Sequence 1: NP_524009.2
• Gene: alphaTub67C / 39130
• FlyBaseID: FBgn0087040
• Length: 462
• Species: Drosophila melanogaster
• Sequence 2: NP_057346.1
• Gene: TUBE1 / 51175
• HGNCID: 20775
• Length: 475
• Species: Homo sapiens
• Alignment Length: 485
• Identity: 136/485 - (28%)
• Similarity: 243/485 - (50%)
• Gaps: 67/485 - (13%)

  Fly     1 MREVVSIQIGQCGIQIGNACWELYLLEH-GINLDG-----------SLKTKEELTASGSSASVGH 53
            |.:.|.:|:||||.|||...|:|.|.|| .:|..|           ::.|:  :...|.|.|.|.
Human     1 MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISSFFRNVDTR--VVGDGGSISKGK 63

  Fly    54 DTSANDARTFFTETGNGKQVPRSIFVDLEPTVIDDVRNGCMRELYHPEQLISGKEDAANNYARGR 118
            ..|..               .|::.:|:|..|::::..|.:|:::..:|||:....:.||:|.|.
Human    64 ICSLK---------------ARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGH 113

  Fly   119 YSIGKEVIDRVTSRLQKIAEQCDSLQGFLIFHSLGGGTGSGFTSLLVERLSTDYSKKCKLDFAVY 183
            ...|....|::..:.:|.||.||.||.|.|.||:|||||||..:.|::.|..::.:..:...::|
Human   114 KVFGSLYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIY 178

  Fly   184 PSPKVSTAVVEPYNALLTTHSTMDHSDCVFMVDNEAIYDICN----------------------N 226
            ||.: ...:..|||::|......:|:|||..:||::::||.:                      :
Human   179 PSGE-DDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSLVTS 242

  Fly   227 SLGVDRPAYRN----LNRLIAQIVSSTTASLRFSGSMNVDLNEFQTNLVPFPRIHFPLVAYAPLM 287
            |.|..:..::.    :|.::|.::.:.|:|.||.||:|:||||...||||||::|:.:.:..||.
Human   243 SSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYLVSSLTPLY 307

  Fly   288 SAERSAHEQHAITTLTNACFESSNMMVKCDPRAGKFMACCMLYRGDVVPKDVNAAVSAIKSKRHI 352
            :..........:..:.:..|...:.:::.||:...::||.::.||:|...|:...:..:|..  :
Human   308 TLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQISDLRRNIERLKPS--L 370

  Fly   353 QFVDWCPTGFKIGINYEKPAFVPDGDLAKTSRACCMLSNTTAISVAFSNLSYKFDLMFKKRAFVH 417
            |||.|...|:|..:....|        ...|.:...|:|.|.:...|..|..:|..::||:|.:|
Human   371 QFVSWNQEGWKTSLCSVPP--------VGHSHSLLALANNTCVKPTFMELKERFMRLYKKKAHLH 427

  Fly   418 WYVG-EGMEEGEFTEARENIAVLERDFEEV 446
            .|:. |||||..||||..:::.|.::::::
Human   428 HYLQVEGMEESCFTEAVSSLSALIQEYDQL 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub67C	NP_524009.2	alpha_tubulin	2..446	CDD:276955	135/482 (28%)
TUBE1	NP_057346.1	epsilon_tubulin	2..457	CDD:276959	135/482 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900