DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTub67C and tuba7l

DIOPT Version :9

Sequence 1:	NP_524009.2	Gene:	alphaTub67C / 39130	FlyBaseID:	FBgn0087040	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	XP_021334828.1	Gene:	tuba7l / 431777	ZFINID:	ZDB-GENE-040704-78	Length:	468	Species:	Danio rerio

Alignment Length:	462	Identity:	313/462 - (67%)
Similarity:	377/462 - (81%)	Gaps:	15/462 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 REVVSIQIGQCGIQIGNACWELYLLEHGINLDGSLKTKEELTASGSSASVGHDTSANDA--RTFF 64
            ||.:|:.:||.|:||||||||||.|||||..||.:.:             .|.||..|.  .|||
Zfish    20 RECISVHVGQAGVQIGNACWELYCLEHGIQADGHMPS-------------DHTTSGGDQSFNTFF 71

  Fly    65 TETGNGKQVPRSIFVDLEPTVIDDVRNGCMRELYHPEQLISGKEDAANNYARGRYSIGKEVIDRV 129
            :|||.||.|||::||||||||:|:||.|..|:|:||||||:||||||||||||.|:||||::|.|
Zfish    72 SETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLV 136

  Fly   130 TSRLQKIAEQCDSLQGFLIFHSLGGGTGSGFTSLLVERLSTDYSKKCKLDFAVYPSPKVSTAVVE 194
            ..|::|:.:||..|||||||||.||||||||.|||:||||.||.||.||:|||||:|:|||||||
Zfish   137 LDRVRKLCDQCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKAKLEFAVYPAPQVSTAVVE 201

  Fly   195 PYNALLTTHSTMDHSDCVFMVDNEAIYDICNNSLGVDRPAYRNLNRLIAQIVSSTTASLRFSGSM 259
            |||::||||:|::||||.||||||||||||..:|.::||.|.||||||.|||||.||||||.|::
Zfish   202 PYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGAL 266

  Fly   260 NVDLNEFQTNLVPFPRIHFPLVAYAPLMSAERSAHEQHAITTLTNACFESSNMMVKCDPRAGKFM 324
            ||||.||||||||:||||||||.|||::|||::.|||.::..:||||||.:|.|||||||.||:|
Zfish   267 NVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLSVVEITNACFEPANQMVKCDPRHGKYM 331

  Fly   325 ACCMLYRGDVVPKDVNAAVSAIKSKRHIQFVDWCPTGFKIGINYEKPAFVPDGDLAKTSRACCML 389
            ||||||||||||||||||:.:||:||.||||||||||||:||||:.|..||.|||||..||.|||
Zfish   332 ACCMLYRGDVVPKDVNAAIGSIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCML 396

  Fly   390 SNTTAISVAFSNLSYKFDLMFKKRAFVHWYVGEGMEEGEFTEARENIAVLERDFEEVGLDNAEEG 454
            ||||||:.|::.|.:|||||:.||||||||||||||||||.||||::|.||:|:||||:|..:..
Zfish   397 SNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFAEAREDLAALEKDYEEVGVDTIDGE 461

  Fly   455 GDEDFDE 461
            |:.:.:|
Zfish   462 GEAEGEE 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub67C	NP_524009.2	alpha_tubulin	2..446	CDD:276955	307/445 (69%)
tuba7l	XP_021334828.1	PTZ00335	20..459	CDD:185562	311/451 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D275336at33208
OrthoFinder	1	1.000	-	-		FOG0000082
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100108
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820