DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTub67C and Tube1

DIOPT Version :9

Sequence 1:	NP_524009.2	Gene:	alphaTub67C / 39130	FlyBaseID:	FBgn0087040	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	XP_006256590.1	Gene:	Tube1 / 361856	RGDID:	1306048	Length:	475	Species:	Rattus norvegicus

Alignment Length:	483	Identity:	144/483 - (29%)
Similarity:	244/483 - (50%)	Gaps:	63/483 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MREVVSIQIGQCGIQIGNACWELYLLEH-GINLDG-------SLKTKEELTASGSSASV--GHDT 55
            |.:.|.:|:||||.|||...|:|.|.|| .:|..|       |.....:..|.|...|:  |..:
  Rat     1 MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDDAISSFFRNVDTRAVGDCGSISKGRIS 65

  Fly    56 SANDARTFFTETGNGKQVPRSIFVDLEPTVIDDVRNGCMRELYHPEQLISGKEDAANNYARGRYS 120
            |..               .|::.:|:|..|::::..|.:|:::..:|||:....:.||:|.|...
  Rat    66 SLK---------------ARAVLIDMEEGVVNEILQGPLRDVFDSKQLITDISGSGNNWAVGHKV 115

  Fly   121 IGKEVIDRVTSRLQKIAEQCDSLQGFLIFHSLGGGTGSGFTSLLVERLSTDYSKKCKLDFAVYPS 185
            .|....:::..:|:|.||.||.||.|.|.||:|||||||..:.|::.|..::.:..:...|||||
  Rat   116 FGSLYREQILEKLRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTAVYPS 180

  Fly   186 PKVSTAVVEPYNALLTTHSTMDHSDCVFMVDNEAIYDICN------NS--LGV------------ 230
            .: ...:..|||::|......:|:|||..:||::::||.:      ||  ||.
  Rat   181 SE-DDVITSPYNSMLAMKELSEHADCVLPIDNQSLFDIISKIDLVVNSGKLGSAVKPKSLITSNT 244

  Fly   231 ------DRPAYRNLNRLIAQIVSSTTASLRFSGSMNVDLNEFQTNLVPFPRIHFPLVAYAPLMSA 289
                  .:..:..:|.::|.::.|.|:|.||.||:|:||||...||||||::|:.:.:..||.:.
  Rat   245 GPVKKRHKKPFDAMNNIVANLLLSLTSSARFEGSLNMDLNEISMNLVPFPQLHYLVSSLTPLYTL 309

  Fly   290 ERSAHEQHAITTLTNACFESSNMMVKCDPRAGKFMACCMLYRGDVVPKDVNAAVSAIKSKRHIQF 354
            .........:..:.:..|...:.:::.|||.|.::||.::.||:|...|:...:..:|..  :||
  Rat   310 ADVNIPPRRLDQMFSDAFSKGHQLLQADPRHGLYLACALIVRGEVQISDLRRNIERLKPA--LQF 372

  Fly   355 VDWCPTGFKIGINYEKPAFVPDGDLAKTSRACCMLSNTTAISVAFSNLSYKFDLMFKKRAFVHWY 419
            |.|...|:|..:....|...|...||        |:|.|.:...|..|..:|..::||:|.:|.|
  Rat   373 VSWNQEGWKTSLCSVPPVGHPHSLLA--------LANNTCVKPTFLELRERFMRLYKKKAHLHHY 429

  Fly   420 VG-EGMEEGEFTEARENIAVLERDFEEV 446
            :. :||||..||||..:::.|.:::.::
  Rat   430 LQVDGMEESTFTEAVSSLSALIQEYSDL 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub67C	NP_524009.2	alpha_tubulin	2..446	CDD:276955	143/480 (30%)
Tube1	XP_006256590.1	PTZ00387	1..470	CDD:240395	144/483 (30%)
Tube1	XP_006256590.1	epsilon_tubulin	2..457	CDD:276959	143/480 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900