DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTub67C and tube1

DIOPT Version :9

Sequence 1:	NP_524009.2	Gene:	alphaTub67C / 39130	FlyBaseID:	FBgn0087040	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_001016136.1	Gene:	tube1 / 100488997	XenbaseID:	XB-GENE-492734	Length:	472	Species:	Xenopus tropicalis

Alignment Length:	492	Identity:	140/492 - (28%)
Similarity:	248/492 - (50%)	Gaps:	70/492 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MREVVSIQIGQCGIQIGNACWELYLLEH-GINLDG-----------SLKTKEELTASGSSASVGH 53
            |.:.:.:|:||||.|||...|:|.|.|| .:|..|           ::.|:.|  |.|:.|..|.
Frog     1 MTQSIVVQVGQCGNQIGCRFWDLALREHASVNKKGIFDEALCSFFRNVDTRAE--AGGADAQRGK 63

  Fly    54 DTSANDARTFFTETGNGKQVPRSIFVDLEPTVIDDVRNGCMRELYHPEQLISGKEDAANNYARGR 118
            ..|..               .|::.:|:|..|::::..|.:|:|:..:|||:....:.||:|.|.
Frog    64 ICSLK---------------ARAVLIDMEEGVVNEILQGPLRDLFDSKQLITDVSGSGNNWAVGH 113

  Fly   119 YSIGKEVIDRVTSRLQKIAEQCDSLQGFLIFHSLGGGTGSGFTSLLVERLSTDYSKKCKLDFAVY 183
            ...|.:..:.:...|::.|||||.||.|.:.||:|||||||..:.::..|..::.:..:...:||
Frog   114 KLYGGQYREHIVENLRRTAEQCDCLQCFFVIHSMGGGTGSGLGTFVLNVLEEEFPEVYRFVTSVY 178

  Fly   184 PSPKVSTAVVEPYNALLTTHSTMDHSDCVFMVDNEAIYDICN----------------NSL---- 228
            ||.: ...:..|||::|......:|:|||..::|:|:.||.|                |||
Frog   179 PSAE-DDVITSPYNSVLAMKELTEHADCVLPIENQALVDIVNKINQMANTGKLGNVKSNSLLTSN 242

  Fly   229 --GV---DRPAYRNLNRLIAQIVSSTTASLRFSGSMNVDLNEFQTNLVPFPRIHFPLVAYAPLMS 288
              |:   ::| :..:|.::|.::.:.|:|.||.||:|:||||...||||||::|:...:..||.:
Frog   243 KGGIKENEKP-FDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYLTSSLTPLYT 306

  Fly   289 AERSAHEQHAITTLTNACFESSNMMVKCDPRAGKFMACCMLYRGDVVPKDVNAAVSAIKSKRHIQ 353
            ..........:..:.:..|...:.:::.||:...::||.::.||:|...|:...:..:|.  .:|
Frog   307 LADVNVPTRRLDQMFSDAFSKDHQLIRADPKHSLYLACALMVRGNVQISDLRRNIERLKP--FLQ 369

  Fly   354 FVDWCPTGFKIGINYEKPAFVPDGDLAKTSRACCMLSNTTAISVAFSNLSYKFDLMFKKRAFVHW 418
            ||.|...|:|.|:....|        ...|.:...|:|.|.:...|..|..:|..:::|:|.:|.
Frog   370 FVSWNQEGWKTGLCSVPP--------VGHSHSLLALANNTCVKPTFIELRDRFSKLYRKKAHLHH 426

  Fly   419 YVG-EGMEEGEFTEARENIAVLERDFEEVGLDNAEEG 454
            |:. :|||:..||||..:::.|..::.::   :|.:|
Frog   427 YMQVDGMEQHCFTEAISSLSSLIEEYSQL---DASKG 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub67C	NP_524009.2	alpha_tubulin	2..446	CDD:276955	137/481 (28%)
tube1	NP_001016136.1	PTZ00387	1..456	CDD:240395	138/486 (28%)
tube1	NP_001016136.1	epsilon_tubulin	2..455	CDD:276959	137/481 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000