Protein Alignment CG16717 and MPPED2

DIOPT Version :10

• Sequence 1: NP_648343.1
• Gene: CG16717 / 39129
• FlyBaseID: FBgn0036028
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_001575.1
• Gene: MPPED2 / 744
• HGNCID: 1180
• Length: 294
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 137/302 - (45%)
• Similarity: 182/302 - (60%)
• Gaps: 29/302 - (9%)

  Fly     3 VPVHPLSQDPTAAWREISKTQRVIK---VTMKPPTTTVAPNKA---RVVCMSDTHSLTPYIKFDI 61
            :.|...|.:||.|:...:..|...:   |.|..|.....|..|   |.||:|||||.|..|:  :
Human    13 ITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQ--M 75

  Fly    62 PDGDIFIHAGDFTKCGQLEEVEEFNTWIGALPHRHKIVIAGNHELSFDRTFTHPFQKSKSHASSS 126
            |.|||.:|.||||:.|...||::||.|:|.||:.:||||||||||:||:.|.....|...:.
Human    76 PYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVKQDYYR--- 137

  Fly   127 KHTGMSILDDLPTLGNAK-ENLESAVQTQNVRDVLTNCRYLEDELLEIWGIQIYGSPWQPEFCRW 190
                      .|::...| |:.:      ||:.:|||..||:|..:.:.|.:|||:||.|.|..|
Human   138 ----------FPSVSKLKPEDFD------NVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGW 186

  Fly   191 AFNVPRGTACLDKWNQIPEGIDILVTHTPPVGHGDLCCSGV-RAGCVELLSTVQQRVRPKYHVFG 254
            .||:|||.:.|||||.||||||||:||.||:|..|.....: |.||||||:|||:|||||.||||
Human   187 GFNLPRGQSLLDKWNLIPEGIDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFG 251

  Fly   255 HVHEGYGITSDGRIIFVNASTCDINYLPNNAPIVFDVTLPPG 296
            .:||||||.:||...::|||||.:::.|.|.||:||:..|.|
Human   252 GIHEGYGIMTDGYTTYINASTCTVSFQPTNPPIIFDLPNPQG 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16717	NP_648343.1	MPP_239FB	43..274	CDD:277325	114/232 (49%)
MPPED2	NP_001575.1	MPP_239FB	59..271	CDD:277325	114/232 (49%)