DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16717 and mpped2a

DIOPT Version :9

Sequence 1:	NP_648343.1	Gene:	CG16717 / 39129	FlyBaseID:	FBgn0036028	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_001017735.1	Gene:	mpped2a / 550430	ZFINID:	ZDB-GENE-050417-241	Length:	294	Species:	Danio rerio

Alignment Length:	299	Identity:	134/299 - (44%)
Similarity:	178/299 - (59%)	Gaps:	27/299 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VPVHPLSQDPTAAWREISKTQRVIK---VTMKPPTTTVAP---NKARVVCMSDTHSLTPYIKFDI 61
            :.|...|.:||.|....:..|...:   |.|..|.:...|   ...|.||:|||||.|..|:  :
Zfish    13 ISVDEYSSNPTQALTHYNINQSRFQPPHVHMVDPISYDTPKPGGHTRFVCVSDTHSRTDGIQ--M 75

  Fly    62 PDGDIFIHAGDFTKCGQLEEVEEFNTWIGALPHRHKIVIAGNHELSFDRTFTHPFQKSKSHASSS 126
            |.||:.:|.||||:.|...||::||.|:|:||:..|:||||||||:||:.|.....|...:.
Zfish    76 PYGDVLLHTGDFTELGLPSEVKKFNDWLGSLPYEFKVVIAGNHELTFDKDFMTELVKQDYYR--- 137

  Fly   127 KHTGMSILDDLPTLGNAKENLESAVQTQNVRDVLTNCRYLEDELLEIWGIQIYGSPWQPEFCRWA 191
                      .|::...|..     ...||:.:||||.||:|..:.:.|.:|||:||.|.|..|.
Zfish   138 ----------FPSVSKLKPK-----DFDNVQSLLTNCVYLQDSDVTVKGFRIYGTPWTPWFNGWG 187

  Fly   192 FNVPRGTACLDKWNQIPEGIDILVTHTPPVGHGDLCCSGV-RAGCVELLSTVQQRVRPKYHVFGH 255
            ||:|||.:.|||||.||||:|||:||.||:|..|.....: |.||||||:|||:|||||.||||.
Zfish   188 FNLPRGQSLLDKWNLIPEGVDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGG 252

  Fly   256 VHEGYGITSDGRIIFVNASTCDINYLPNNAPIVFDVTLP 294
            :||||||.:||...|:|||||.:::.|.|.|||||:..|
Zfish   253 IHEGYGIMTDGYTTFINASTCTVSFQPTNPPIVFDLPNP 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16717	NP_648343.1	MPP_239FB	43..274	CDD:277325	112/231 (48%)
mpped2a	NP_001017735.1	MPP_239FB	59..271	CDD:277325	112/231 (48%)
		Metallophos	59..255	CDD:278574	102/215 (47%)
		PHA03008	<112..255	CDD:165309	74/160 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595033
Domainoid	1	1.000	207	1.000	Domainoid score	I2827
eggNOG	1	0.900	-	-		E1_KOG3947
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	253	1.000	Inparanoid score	I3176
OMA	1	1.010	-	-		QHG57786
OrthoDB	1	1.010	-	-		D1301937at2759
OrthoFinder	1	1.000	-	-		FOG0002700
OrthoInspector	1	1.000	-	-		otm25229
orthoMCL	1	0.900	-	-		OOG6_101637
Panther	1	1.100	-	-	O	PTHR12905
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5633
SonicParanoid	1	1.000	-	-		X1798
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800