DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16717 and mpped2

DIOPT Version :9

Sequence 1:	NP_648343.1	Gene:	CG16717 / 39129	FlyBaseID:	FBgn0036028	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_001017101.1	Gene:	mpped2 / 549855	XenbaseID:	XB-GENE-1016332	Length:	294	Species:	Xenopus tropicalis

Alignment Length:	300	Identity:	136/300 - (45%)
Similarity:	181/300 - (60%)	Gaps:	29/300 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VPVHPLSQDPTAAWREISKTQRVIK---VTMKPPTTTVAPNKA---RVVCMSDTHSLTPYIKFDI 61
            :.|...|.:||.|:...:..|...:   |.|..|.....|..|   |.||:|||||.|..|:  :
Frog    13 ITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCVSDTHSRTDGIQ--M 75

  Fly    62 PDGDIFIHAGDFTKCGQLEEVEEFNTWIGALPHRHKIVIAGNHELSFDRTFTHPFQKSKSHASSS 126
            |.|||.:|.||||:.|...||::||.|:|.||:.:||||||||||:||:.|.....|...:.
Frog    76 PYGDILLHTGDFTELGLPSEVKKFNDWLGTLPYEYKIVIAGNHELTFDKEFMADLVKQDYYR--- 137

  Fly   127 KHTGMSILDDLPTLGNAK-ENLESAVQTQNVRDVLTNCRYLEDELLEIWGIQIYGSPWQPEFCRW 190
                      .|::...| |:.:      ||:.:|||..||:|..:.:.|.:|||:||.|.|..|
Frog   138 ----------FPSVSKLKPEDFD------NVQTLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGW 186

  Fly   191 AFNVPRGTACLDKWNQIPEGIDILVTHTPPVGHGDLCCSGV-RAGCVELLSTVQQRVRPKYHVFG 254
            .||:|||.:.|||||.:|||||||:||.||:|..|.....: |.||||||:|||:|||||.||||
Frog   187 GFNLPRGQSLLDKWNLVPEGIDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFG 251

  Fly   255 HVHEGYGITSDGRIIFVNASTCDINYLPNNAPIVFDVTLP 294
            .:||||||.:||...:||||||.:::.|.|.||:||:..|
Frog   252 GIHEGYGIMTDGYTTYVNASTCTVSFQPINPPIIFDLPNP 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16717	NP_648343.1	MPP_239FB	43..274	CDD:277325	114/232 (49%)
mpped2	NP_001017101.1	MPP_239FB	59..271	CDD:277325	114/232 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	210	1.000	Domainoid score	I2765
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I3109
OMA	1	1.010	-	-		QHG57786
OrthoDB	1	1.010	-	-		D1301937at2759
OrthoFinder	1	1.000	-	-		FOG0002700
OrthoInspector	1	1.000	-	-		otm48275
Panther	1	1.100	-	-	O	PTHR12905
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5633
SonicParanoid	1	1.000	-	-		X1798
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.110