Protein Alignment CNMaR and Gpr142

DIOPT Version :10

• Sequence 1: NP_001027122.2
• Gene: CNMaR / 39127
• FlyBaseID: FBgn0053696
• Length: 480
• Species: Drosophila melanogaster
• Sequence 2: NP_001385802.1
• Gene: Gpr142 / 501735
• RGDID: 1559926
• Length: 348
• Species: Rattus norvegicus
• Alignment Length: 406
• Identity: 75/406 - (18%)
• Similarity: 122/406 - (30%)
• Gaps: 138/406 - (33%)

  Fly    65 YIPVLCCTGSIGNILSVFVFFRTKLR-KLSSSFYLAALAVSDTCFLAGLFAQWLNFL-------- 120
            |..||...|...|:|:..|..|..:| |..|..||.||..||  .:..:...::.||
  Rat    52 YYSVLLSLGLPVNVLTTVVLARLAVRTKKPSYHYLLALTASD--IVTQVVIVFIGFLLQGAVLAR 114

  Fly   121 ---NVDIYNQNYFCQFFTFFSYLASFCSVWFVVAFTVERFIAVIYPLKRQTMCTVRRAKIVLFCL 182
               ...:...|       ...:.|:..|||..|.|||:|:.|:..||:.:...:..|....:..:
  Rat   115 QVPQAVVRTAN-------ILEFAANHASVWIAVLFTVDRYNALCRPLRHRATSSPGRTHRAIAAV 172

  Fly   183 TLVGCLHCLPYI-------VIAKPVFMPKLNTTICDLNSEYKEQLALFNYWDTIVVYAVPFTTIA 240
            ..|..|..:|:.       ....|..|.|                 |..:...::||.:|.....
  Rat   173 LSVTLLTGIPFYWWLDVWRDADPPSTMDK-----------------LLKWAHCLIVYFIPCNVFL 220

  Fly   241 VLNTCTGCTVWKFATVRRTLTMHKMKPQTNSMPSNSSNSSGGASSAVASYRLSASLKRQKSTGTH 305
            |.|:         |.:.|                                     |:::...|..
  Rat   221 VTNS---------AIILR-------------------------------------LRKRGQRGLQ 239

  Fly   306 PSGQHNVANRQTDDQEQQQQSQQHQINNCQHHCEITQKPARRKVQNSSQLKVTKMLLIVSTVFVC 370
            |                                              ...|.|.:||.|:::|..
  Rat   240 P----------------------------------------------WMSKSTAILLGVTSLFAL 258

  Fly   371 LNLPSCLLRIEAYWETESARNQNSTIALQYIFHAFFITNFGINFVLYCVSGQNFRKAVLSIFRRV 435
            |..|...:.:...:.....|:....:||. |.:...:.|..:||.|||...:.||..|..:.:.|
  Rat   259 LWAPRISVMLYHLYVAPVHRDWRVHLALD-IANMLAMLNTAVNFGLYCFISKTFRATVRQVIQDV 322

  Fly   436 SSAQREAGNTQVTVSE 451
            ..:.......:.||:|
  Rat   323 HMSCALKSQPKGTVTE 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CNMaR	NP_001027122.2	7tmA_FMRFamide_R-like	60..428	CDD:410630	70/381 (18%)
		TM helix 1	61..87	CDD:410630	7/21 (33%)
		TM helix 2	94..119	CDD:410630	7/24 (29%)
		TM helix 3	131..161	CDD:410630	10/29 (34%)
		TM helix 4	173..193	CDD:410630	3/19 (16%)
		TM helix 5	220..245	CDD:410630	6/24 (25%)
		TM helix 6	352..382	CDD:410630	8/29 (28%)
		TM helix 7	396..421	CDD:410630	9/24 (38%)
Gpr142	NP_001385802.1	7tm_GPCRs	47..315	CDD:475119	70/381 (18%)
		TM helix 1	49..73	CDD:410628	7/20 (35%)
		TM helix 2	83..105	CDD:410628	6/23 (26%)
		TM helix 3	122..144	CDD:410628	7/28 (25%)
		TM helix 4	167..183	CDD:410628	2/15 (13%)
		TM helix 5	201..224	CDD:410628	6/39 (15%)
		TM helix 6	246..268	CDD:410628	7/21 (33%)
		TM helix 7	283..308	CDD:410628	9/25 (36%)