Protein Alignment CNMaR and Gpr139

DIOPT Version :9

• Sequence 1: NP_001027122.2
• Gene: CNMaR / 39127
• FlyBaseID: FBgn0053696
• Length: 480
• Species: Drosophila melanogaster
• Sequence 2: NP_001019412.1
• Gene: Gpr139 / 293545
• RGDID: 1311729
• Length: 345
• Species: Rattus norvegicus
• Alignment Length: 457
• Identity: 92/457 - (20%)
• Similarity: 161/457 - (35%)
• Gaps: 144/457 - (31%)

  Fly    32 EYNTTEMDANESA-GEDEEMLRIAFFIGHFVHQYYIPVLCCTGSIGNILSVFVFFRTKLRKLSSS 95
            |:....:.||.|| |           :| ||...|...|.|.|...|||:|.:..:...|:..||
  Rat     2 EHTHAHLAANSSACG-----------LG-FVPVVYYSFLLCLGLPANILTVIILSQLVARRQKSS 54

  Fly    96 F-YLAALAVSDTCFLAGLFAQWLNFLNVDIYNQNYFC----------QFFTFFSYLASFCSVWFV 149
            : ||.|||.:|...|  .|..:::||..|      |.          :......:.:...|:|..
  Rat    55 YNYLLALAAADILVL--FFIVFVDFLLED------FILTMQMPPIPDKIIEVLEFSSIHTSIWIT 111

  Fly   150 VAFTVERFIAVIYPLKRQTMCTVRRAKIVLFCLTLVGCLHCLPYIVIAKPVFMPKLNTTICDLNS 214
            |..||:|:|||.:|||..|:....|.:.|:..:.:...|..:||      .:.|.:.|.  |..|
  Rat   112 VPLTVDRYIAVCHPLKYHTVSYPARTRKVILSVYITCFLTSIPY------YWWPNIWTE--DYIS 168

  Fly   215 EYKEQLALFNYWDTIVVYAVPFTTIAVLNTCTGCTVWKFATVRRTLTMHKMKPQTNSMPSNSSNS 279
            .....:.::.:..|  ||.||.:...:||               ::.::|::.::|
  Rat   169 TSMHHVLVWIHCFT--VYLVPCSIFFILN---------------SIIVYKLRRKSN--------- 207

  Fly   280 SGGASSAVASYRLSASLKRQKSTGTHPSGQHNVANRQTDDQEQQQQSQQHQINNCQHHCEITQKP 344
                      :||     |..|||
  Rat   208 ----------FRL-----RGYSTG----------------------------------------- 216

  Fly   345 ARRKVQNSSQLKVTKMLLIVSTVFVCLNLPSCLLRIEAYWETESARNQNSTIA--LQYIFHAFFI 407
                       |.|.:|..::::|..|..|..::.:   :....|..||..:.  :..:.:...:
  Rat   217 -----------KTTAILFTITSIFATLWAPRIIMIL---YHLYGAPIQNPWLVHIMLDVANMLAL 267

  Fly   408 TNFGINFVLYCVSGQNFRKAVLSIFRRVSSAQREA------GNTQVTVSEYCRNTGTSTRRRMMT 466
            .|..|||.|||...:.||....:..:.:...|::.      .|..:|.|.:.....:...:.::.
  Rat   268 LNTAINFFLYCFISKRFRTMAAATLKALFKCQKQPVQFYTNHNFSITSSPWISPANSHCIKMLVY 332

  Fly   467 QH 468
            |:
  Rat   333 QY 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CNMaR	NP_001027122.2	7tm_4	73..>262	CDD:304433	49/199 (25%)
Gpr139	NP_001019412.1	7tmA_GPR139	19..288	CDD:320585	80/380 (21%)
		TM helix 1	21..45	CDD:320585	8/23 (35%)
		TM helix 2	55..77	CDD:320585	8/23 (35%)
		TM helix 3	94..116	CDD:320585	3/21 (14%)
		TM helix 4	139..155	CDD:320585	2/15 (13%)
		TM helix 5	173..196	CDD:320585	7/39 (18%)
		TM helix 6	219..241	CDD:320585	5/21 (24%)
		TM helix 7	256..281	CDD:320585	7/24 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351868
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840