DRSC/TRiP Functional Genomics Resources

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Protein Alignment CNMaR and GPR18

DIOPT Version :9

Sequence 1:NP_001027122.2 Gene:CNMaR / 39127 FlyBaseID:FBgn0053696 Length:480 Species:Drosophila melanogaster
Sequence 2:NP_001091670.1 Gene:GPR18 / 2841 HGNCID:4472 Length:331 Species:Homo sapiens


Alignment Length:247 Identity:45/247 - (18%)
Similarity:96/247 - (38%) Gaps:54/247 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 NESAGEDEEMLRIAFF-----IGHFVHQYYIPVLCCTGSIGNILSVFVFFRTKLRKLSSSFYLAA 100
            |.|..::.::..:.|:     ||.||               ||.:::||..|..::.:.:.|:..
Human    14 NSSHPDEYKIAALVFYSCIFIIGLFV---------------NITALWVFSCTTKKRTTVTIYMMN 63

  Fly   101 LAVSDTCFLAGLFAQWLNFLNVDIYNQNYFCQFFTFFSYLASFCSVWFVVAFTVERFIAVI---Y 162
            :|:.|..|:..|..:...:...:.....||||.....:......::|.:...:.:|::|::   |
Human    64 VALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKY 128

  Fly   163 PLKRQTMCTVRRAKIVLFCLTLVGCLHCLPYIVIAK-------PVFMPKLNTTICDLNSEYKEQL 220
            ..:.:..|....|.:.::.:||.   ...|.:::.|       |....|::..|      |.:.:
Human   129 AKELKNTCKAVLACVGVWIMTLT---TTTPLLLLYKDPDKDSTPATCLKISDII------YLKAV 184

  Fly   221 ALFNYWDTIVVYAVPFTTIAVLNTCTGCTVWKFATVRRTLTMH----KMKPQ 268
            .:.|.......:.:|      |....||    :..:...| :|    |:||:
Human   185 NVLNLTRLTFFFLIP------LFIMIGC----YLVIIHNL-LHGRTSKLKPK 225

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CNMaRNP_001027122.2 7tm_4 73..>262 CDD:304433 34/198 (17%)
GPR18NP_001091670.1 7tmA_NAGly_R_GPR18 23..297 CDD:320294 43/238 (18%)
TM helix 1 23..50 CDD:320294 9/41 (22%)
TM helix 2 57..82 CDD:320294 5/24 (21%)
TM helix 3 94..124 CDD:320294 5/29 (17%)
TM helix 4 136..158 CDD:320294 5/24 (21%)
TM helix 5 184..213 CDD:320294 5/38 (13%)
TM helix 6 225..255 CDD:320294 0/1 (0%)
TM helix 7 265..290 CDD:320294
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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