DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CNMaR and T02D1.4

DIOPT Version :9

Sequence 1:	NP_001027122.2	Gene:	CNMaR / 39127	FlyBaseID:	FBgn0053696	Length:	480	Species:	Drosophila melanogaster
Sequence 2:	NP_503104.2	Gene:	T02D1.4 / 187984	WormBaseID:	WBGene00011371	Length:	446	Species:	Caenorhabditis elegans

Alignment Length:	295	Identity:	69/295 - (23%)
Similarity:	116/295 - (39%)	Gaps:	73/295 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ITSSSGNITATTEADFSSSLGESNVTEYNTTEMDANESAGEDEEMLRIA----------FFIGH- 59
            |.|||.:|::..||           |:...|||....|..:.||..|||          :.:|:
Worm    40 INSSSTSISSQEEA-----------TDDPLTEMLDRFSRIQQEECDRIANLCENRQLYTWLVGYG 93

  Fly    60 FVHQYYIPVLCCTGSIGNIL---SVFVFFRTKLRKLSSSFYLAALAVSDTCFL---AGLFAQWLN 118
            |:   ::.:|...|::.|:|   |..:.:...:|.|.:...:.:|.:  .|.|   ..:.:.|.:
Worm    94 FI---FVFLLALFGNVVNLLIYNSDHIKYYIAIRMLCTRLLMNSLTL--ICMLPQALRIVSAWDS 153

  Fly   119 FLNV-DIYNQNYFCQFFTFFSYLASFCSVWFVVAFTVERFIAVIYPLKRQTMCTVRRAKIVLFCL 182
            ..:: :||...|..|.  :|..|..||::|..|..|.|.::.|.:|...:::||.|......|.:
Worm   154 DSHINEIYWVYYPYQI--YFVNLFGFCAMWLTVLMTAECYLHVFFPSHSKSLCTKRNLSRSYFII 216

  Fly   183 TLVGCL---------------HC---LPYIVIAKPVFMPKLNTTICDLNSEYKEQLALF-NYWDT 228
            .:||.|               ||   :|.|..::...|      ||      .|::..| |....
Worm   217 LVVGALLALMYKFNRSVTLSTHCNRVIPTIHASEDFVM------IC------LEKIHTFANLLFA 269

  Fly   229 IVVYAVPFTTIAVLNTCTGCTVWKFATVRRTLTMH 263
            |||      .:.:|.......:||....|.....|
Worm   270 IVV------PMGLLLFMAASILWKLVLKRSDFVSH 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CNMaR	NP_001027122.2	7tm_4	73..>262	CDD:304433	48/214 (22%)
T02D1.4	NP_503104.2	7tmA_FMRFamide_R-like	88..377	CDD:320109	52/236 (22%)
		TM helix 1	90..114	CDD:320109	6/26 (23%)
		TM helix 2	122..145	CDD:320109	5/24 (21%)
		TM helix 3	166..188	CDD:320109	7/23 (30%)
		TM helix 4	211..227	CDD:320109	4/15 (27%)
		TM helix 5	259..282	CDD:320109	6/28 (21%)
		TM helix 6	304..329	CDD:320109
		TM helix 7	345..370	CDD:320109
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D421120at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920