DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CNMaR and srx-60

DIOPT Version :9

Sequence 1:	NP_001027122.2	Gene:	CNMaR / 39127	FlyBaseID:	FBgn0053696	Length:	480	Species:	Drosophila melanogaster
Sequence 2:	NP_504895.2	Gene:	srx-60 / 187858	WormBaseID:	WBGene00005951	Length:	300	Species:	Caenorhabditis elegans

Alignment Length:	185	Identity:	40/185 - (21%)
Similarity:	75/185 - (40%)	Gaps:	32/185 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 IGNILSVFVFFRT-KLRKLSSSF-YLAAL-----AVSDTCFLAGLFAQWLNFLNVDIYNQ----- 127
            ||::|:..:.... ||..|::|| ||.|.     |:....||       |.|..:.|.:|
Worm    17 IGSVLNFSILIAIYKLPALNNSFGYLTANQAIVDALHSVIFL-------LYFCPMVILDQPIMKS 74

  Fly   128 -NYFCQFFTFFSYLASFCSVWFVVAFTVERFIAVIYPLKRQTMCTVRRAKIVLFCLTLVG-CLHC 190
             ::....|..|.|..|..:.:.:   ::.||.||..|||.:...:.:....::..|.:.. .|..
Worm    75 YSFIVGCFLLFCYELSVLTHFLI---SINRFCAVWVPLKYEKWFSRKNTSSIIILLWIFEVALAI 136

  Fly   191 LPYIVIAKPVFMPKL------NTTICDLNSEYKEQLALFNYWDTIVVYAVPFTTI 239
            :.|.::....::.::      ||..|...:.|.:.:.  |.....:|..|..:|:
Worm   137 VFYQILCHVAYLEEIHFIQFTNTKFCGFVAWYDDFVK--NSVIIAIVVCVDISTV 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CNMaR	NP_001027122.2	7tm_4	73..>262	CDD:304433	40/185 (22%)
srx-60	NP_504895.2	TM helix 1	8..31	CDD:381740	3/13 (23%)
		7TM_GPCR_Srx	12..266	CDD:370981	40/185 (22%)
		TM helix 2	40..62	CDD:381740	7/28 (25%)
		TM helix 3	77..99	CDD:381740	4/24 (17%)
		TM helix 4	122..147	CDD:381740	3/24 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D421120at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010