Protein Alignment CNMaR and npr-41

DIOPT Version :10

• Sequence 1: NP_001027122.2
• Gene: CNMaR / 39127
• FlyBaseID: FBgn0053696
• Length: 480
• Species: Drosophila melanogaster
• Sequence 2: NP_496459.2
• Gene: npr-41 / 181927
• WormBaseID: WBGene00007146
• Length: 394
• Species: Caenorhabditis elegans
• Alignment Length: 458
• Identity: 94/458 - (20%)
• Similarity: 166/458 - (36%)
• Gaps: 133/458 - (29%)

  Fly    28 SNVTEYNTTEMDANESAGEDEEMLRIAFFIGHFVHQYYIPVLCCTGSIGNILSVFVFFRTK-LRK 91
            ||:|.:.           .||:.:.|.::....|    :||:...|...|:|::.|....| .|:
 Worm    26 SNITHHE-----------HDEQSISIVWWSNVAV----LPVIALIGLACNLLNMAVLTSNKTARR 75

  Fly    92 LSSSFYLAALAVSDTCFLAGLFAQWLNFLNVDIYNQNYFCQFFTFFS----YLASFCSVWF---- 148
            :.|...|.||||.|:.||  :||. |:...:.|.:..:...|..|:|    |:.:..|.::
 Worm    76 IPSWNLLIALAVCDSLFL--IFAT-LDVTPLSIPSLAFSTSFNHFYSRIVLYIRTLASTFYKSSV 137

  Fly   149 --VVAFTVERFIAVIYPLKRQTMCTVRRAKIVLFCLTLVGCLHCLPYIVIAKPVFMPKLNTTI-C 210
              ||||.:||::.|:.||.....||.|.:|..:....::..|..:.:         |....|| |
 Worm   138 LIVVAFNIERYLCVVCPLNSHRWCTSRNSKNAIATAIVLSFLCSIQW---------PLAYDTIRC 193

  Fly   211 -DLNSEYKEQLALFNYWDTIVVY--AVPFTTIAVLNTCTGCTVWKFATVRRTLTMHKMKPQTNSM 272
             :.||.....:.|.:....:.:|  .:.:.::...|                     :.|....:
 Worm   194 FESNSNQYYYVILMSTNRALQIYYRTMDYVSLFAFN---------------------VLPIIGLL 237

  Fly   273 PSNSSNSSGGASSAVASYRLSASLKRQKSTGTHPSGQHNVANRQTDDQEQQQQSQ---QHQINNC 334
            ..||              |:..:|:|             |.:..:...|:.:.|.   ||.
 Worm   238 YMNS--------------RIIFTLRR-------------VVDEDSRKYEETKLSDGLIQHD---- 271

  Fly   335 QHHCEITQKPARRKVQNSSQLKVTKMLL-IVSTVFVCLNLPSCLLRI--EAYWETESARNQNSTI 396
                          ..|:..::...||. :|..:|.|:. |....||  :.|.:..........:
 Worm   272 --------------AHNNRTMRANAMLFAVVFMLFFCVG-PQAPARILFDMYGQYHPKAILYVCL 321

  Fly   397 ALQYIFHAFFITNFGINFVLYCVSGQNFR---KAVLSIFR----------RVSSAQREAGNTQVT 448
            :.|.:|     .|..:||.||||..:.:|   |..|..|.          :::..|.::.:..||
 Worm   322 SQQLVF-----LNASLNFCLYCVVSKRYRTLMKQTLKKFLHKLEGVDHPFQINLKQTKSSSAHVT 381

  Fly   449 VSE 451
            ..|
 Worm   382 SLE 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CNMaR	NP_001027122.2	7tmA_FMRFamide_R-like	60..428	CDD:410630	82/391 (21%)
		TM helix 1	61..87	CDD:410630	7/25 (28%)
		TM helix 2	94..119	CDD:410630	12/24 (50%)
		TM helix 3	131..161	CDD:410630	11/39 (28%)
		TM helix 4	173..193	CDD:410630	3/19 (16%)
		TM helix 5	220..245	CDD:410630	3/26 (12%)
		TM helix 6	352..382	CDD:410630	8/32 (25%)
		TM helix 7	396..421	CDD:410630	9/24 (38%)
npr-41	NP_496459.2	7tmA_FMRFamide_R-like	43..348	CDD:410630	81/392 (21%)
		TM helix 1	44..70	CDD:410630	7/29 (24%)
		TM helix 2	76..103	CDD:410630	12/29 (41%)
		TM helix 3	122..152	CDD:410630	8/29 (28%)
		TM helix 4	164..184	CDD:410630	3/19 (16%)
		TM helix 5	217..242	CDD:410630	4/59 (7%)
		TM helix 6	275..304	CDD:410630	7/29 (24%)
		TM helix 7	316..341	CDD:410630	9/29 (31%)