DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CNMaR and C24B5.1

DIOPT Version :9

Sequence 1:	NP_001027122.2	Gene:	CNMaR / 39127	FlyBaseID:	FBgn0053696	Length:	480	Species:	Drosophila melanogaster
Sequence 2:	NP_505381.2	Gene:	C24B5.1 / 179301	WormBaseID:	WBGene00016044	Length:	427	Species:	Caenorhabditis elegans

Alignment Length:	379	Identity:	83/379 - (21%)
Similarity:	150/379 - (39%)	Gaps:	84/379 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 VHQYYIPVLCCTGSIGNILSVFVFFRTK--LRKLSSSFYLAALAVSDTCFLAGLFAQWLN----- 118
            ::.:|:|.....|..||.: |::..|:.  |.||.::.||..||...:.||..|...|:.
Worm    77 LYYFYMPFCVFVGLTGNTM-VWILIRSNRMLNKLPTNVYLLCLAAMSSIFLLSLLVFWIEEVAYI 140

  Fly   119 -----FLNVDIYNQNYFCQFFTFFSYLASFCSVWFVVAFTVERFIAVIYPLKRQTMCTVRRAKIV 178
                 |.:..:.|..|.|.|.||.:::..|.|||.:|...:||.: ::|...|...|...||::.
Worm   141 YFYDIFQDSLLRNSYYSCIFNTFLAHVCDFASVWLIVLVGLERLL-LLYRKTRGLTCEKARAQVF 204

  Fly   179 L---FCLTLVGCLHCLPYIVIAKPVFMPKLNTT-ICDLNSEYKEQLALFNYWDTIVVYAVPFTTI 239
            :   |.:...|.:           :|:..::.. .||:..|:..........:||:...||...|
Worm   205 ILLGFAMVFNGWI-----------LFVADMDEEGQCDIKIEFVGMYQTMTIVETIICMLVPSVLI 258

  Fly   240 AVLNTCTGCTVWKFATVRRTLTMH-KMKPQTNSMPSNSSN-----SSGGASSAVASYRLSASLKR 298
            .   ||....|.|       |..| |..|.:.::..|:::     .:...|:.:.||.
Worm   259 I---TCNCLVVSK-------LNSHIKKNPGSPAVSFNTADVVLTTQTSAPSATLKSYT------- 306

  Fly   299 QKSTGTHPSGQHNVANRQTDDQEQQQQSQQHQINNCQHHCEITQKPARRKVQNSSQLKVTKMLLI 363
                        .:::|.:.|.|:..:.                   ::|....:.:::|:.||:
Worm   307 ------------RISSRFSIDVEKAPKK-------------------KKKGIRYTDIQLTRSLLV 340

  Fly   364 VSTVFVCLNLPSCLLRIEAYWETESARNQNSTIALQYIFHAFFITNFGINFVLY 417
            |:..|:.||:|:...||.:.....|.::...| |:....|.|..|:....|.||
Worm   341 VTWAFILLNIPNYGYRIASILFGISEQSSLMT-AISLGAHVFLYTHHAFLFYLY 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CNMaR	NP_001027122.2	7tm_4	73..>262	CDD:304433	51/204 (25%)
C24B5.1	NP_505381.2	7tm_GPCRs	77..404	CDD:391938	83/379 (22%)
		TM helix 1	77..103	CDD:341315	7/26 (27%)
		TM helix 2	111..140	CDD:341315	8/28 (29%)
		TM helix 3	158..185	CDD:341315	11/26 (42%)
		TM helix 4	197..217	CDD:341315	4/19 (21%)
		TM helix 5	239..264	CDD:341315	7/27 (26%)
		TM helix 6	329..359	CDD:341315	10/29 (34%)
		TM helix 7	372..397	CDD:341315	8/23 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG29123
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_107961
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.780