DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18180 and C1S

DIOPT Version :9

Sequence 1:NP_648341.1 Gene:CG18180 / 39125 FlyBaseID:FBgn0036024 Length:264 Species:Drosophila melanogaster
Sequence 2:NP_001725.1 Gene:C1S / 716 HGNCID:1247 Length:688 Species:Homo sapiens


Alignment Length:252 Identity:63/252 - (25%)
Similarity:98/252 - (38%) Gaps:43/252 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 RIVNGYPAPEGKAPYIVGLFIRTDGSNSGAVGAGTIIANDWILTAAHCLTGDYVEIHY-GSNWGW 98
            ||:.|..|.....|:.|..    |...:|    |.:|...|:|||||.:.|:.....| ||....
Human   437 RIIGGSDADIKNFPWQVFF----DNPWAG----GALINEYWVLTAAHVVEGNREPTMYVGSTSVQ 493

  Fly    99 NG--AYRQTVRRDNFISHPDW-----PSQGGR-----DIGLIRTPH-VDFNGLINKIPLPSMNEQ 150
            ..  |..:.:..::...||.|     |.  ||     ||.|:|... |.....::.|.||..:..
Human   494 TSRLAKSKMLTPEHVFIHPGWKLLEVPE--GRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSD 556

  Fly   151 NDRYQDTWCVACGWGGMDNGNLADWLQCVDVQIISNSECEQAYGSVASTD----------MCTRH 205
            .:.......:..|||..:..:.|..|:...:.:....:|::......:.|          :|...
Human   557 YNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAGG 621

  Fly   206 ADGKSVCGGDSGGPLVTHD-NAR----LVGVITFASVSCHDGPSG-YTRVSDYLEWI 256
            ..|...|.|||||.....| |.:    ..|::::.. .|  |..| ||||.:|::||
Human   622 EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGP-QC--GTYGLYTRVKNYVDWI 675

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18180NP_648341.1 Tryp_SPc 35..256 CDD:214473 61/250 (24%)
Tryp_SPc 36..259 CDD:238113 62/251 (25%)
C1SNP_001725.1 CUB 18..129 CDD:238001
FXa_inhibition 143..171 CDD:405372
CUB 175..287 CDD:395345
CCP 294..355 CDD:153056
Sushi 359..421 CDD:395037
Tryp_SPc 438..678 CDD:238113 62/251 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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