DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18180 and CG18754

DIOPT Version :9

Sequence 1:	NP_648341.1	Gene:	CG18180 / 39125	FlyBaseID:	FBgn0036024	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	269	Identity:	62/269 - (23%)
Similarity:	95/269 - (35%)	Gaps:	80/269 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 QGAEGRIVNGYPAPEGKAPYIVGLFIRTDGSNSGAVGAGTIIANDWILTAAHCLTGDYVEIHYGS 94
            :|||...:|.|       |::|.|......|         :|.  ::||||||:.|.|:.
  Fly   107 RGAENAELNEY-------PWMVLLLYENRLS---------LIR--YVLTAAHCVIGGYLT----- 148

  Fly    95 NWGWNGAYRQTVR-----RDNFIS----------------HPDWPSQGG---RDIGLIRTPH-VD 134
               .|....::||     .|...|                |..:.|.||   .||.|:|... |.
  Fly   149 ---QNDLVLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVR 210

  Fly   135 FNGLINKI-------PLPSMNEQNDRYQDTWCVACGWGGMDNGNLADWLQCVDVQIISNSECEQA 192
            :...|..|       ||..:|.|          ..||   |....:..|....|:..:.::|...
  Fly   211 YTKKIQPICLLDAEFPLQDLNLQ----------ISGW---DPTKSSQTLITSTVKERNPADCLNR 262

  Fly   193 YGSVAS-TDMCTRHADGKSVCGGDSGGPLV------THDNARLVGVITFASVSCHDG--PSGYTR 248
            |.|..| :.:|.........|.|.||.|::      ..:...|.|:.::....|:..  |..||:
  Fly   263 YPSFRSASQVCAGGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTK 327

  Fly   249 VSDYLEWIR 257
            :..:.|||:
  Fly   328 IGHFSEWIK 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18180	NP_648341.1	Tryp_SPc	35..256	CDD:214473	57/261 (22%)
CG18180	NP_648341.1	Tryp_SPc	36..259	CDD:238113	59/263 (22%)
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	62/268 (23%)
		Tryp_SPc	108..335	CDD:214473	60/265 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435822
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030