Protein Alignment CG18180 and KLK7

DIOPT Version :10

• Sequence 1: NP_648341.1
• Gene: CG18180 / 39125
• FlyBaseID: FBgn0036024
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 79/266 - (29%)
• Similarity: 125/266 - (46%)
• Gaps: 36/266 - (13%)

  Fly     5 LLTLSAALALVAASPTGLNRTTLLSQGAEG-RIVNGYPAPEGKAPYIVGLFIRTDGSNSGAVGAG 68
            ||.|...|..:|....|        :.|:| :|::|.|...|..|:.|.|.      :...:..|
Human     6 LLPLQILLLSLALETAG--------EEAQGDKIIDGAPCARGSHPWQVALL------SGNQLHCG 56

  Fly    69 TIIAND-WILTAAHCLTGDYVEIHYGSNWGWNGAYR-QTVRRDNFISHPDWPSQGG-RDIGLIR- 129
            .::.|: |:||||||...:|. :|.||:  ..|..| |.::......||.:.:|.. .|:.|::
Human    57 GVLVNERWVLTAAHCKMNEYT-VHLGSD--TLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKL 118

  Fly   130 TPHVDFNGLINKIPLPSMNEQNDRYQDTWCVACGWGGMDNGNL---ADWLQCVDVQIISNSECEQ 191
            ......:.::.|:.|||..|.    ..|.|...|||...:.::   :| |.||||::||..:|.:
Human   119 NSQARLSSMVKKVRLPSRCEP----PGTTCTVSGWGTTTSPDVTFPSD-LMCVDVKLISPQDCTK 178

  Fly   192 AYGSVASTDM-CTRHADG-KSVCGGDSGGPLVTHDNARLVGVITFASVSC--HDGPSGYTRVSDY 252
            .|..:....| |....|. |:.|.||||||||.  ...|.|::::.:..|  .:.|..||:|..:
Human   179 VYKDLLENSMLCAGIPDSKKNACNGDSGGPLVC--RGTLQGLVSWGTFPCGQPNDPGVYTQVCKF 241

  Fly   253 LEWIRD 258
            .:||.|
Human   242 TKWIND 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18180	NP_648341.1	Tryp_SPc	36..259	CDD:238113	71/234 (30%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	68/231 (29%)