Protein Alignment CG18180 and PRSS2

DIOPT Version :10

• Sequence 1: NP_648341.1
• Gene: CG18180 / 39125
• FlyBaseID: FBgn0036024
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 84/288 - (29%)
• Similarity: 131/288 - (45%)
• Gaps: 68/288 - (23%)

  Fly     3 LFLLTLSAALALVAASPTGLNRTTLLSQGAEGRIVNGYPAPEGKAPYIVGLFIRTDGSNSG-AVG 66
            |.:||..||   ..|:|.          ..:.:||.||...|...||.|.|       ||| ...
Human     4 LLILTFVAA---AVAAPF----------DDDDKIVGGYICEENSVPYQVSL-------NSGYHFC 48

  Fly    67 AGTIIANDWILTAAHC--------LTG---DY-----------VEIHYGSNWGWNGAYRQTVRRD 109
            .|::|:..|:::|.||        |:|   :|           :|:..|:        .|.:...
Human    49 GGSLISEQWVVSAGHCYKSAINSKLSGRGCEYHRIQVRLGEHNIEVLEGN--------EQFINAA 105

  Fly   110 NFISHPDWPSQG-GRDIGLIR--TPHVDFNGLINKIPLPSMNEQNDRYQDTWCVACGWGG-MDNG 170
            ..|.||.:.|:. ..||.||:  :|.| .|..::.|.||:....    ..|..:..|||. :.:|
Human   106 KIIRHPKYNSRTLDNDILLIKLSSPAV-INSRVSAISLPTAPPA----AGTESLISGWGNTLSSG 165

  Fly   171 -NLADWLQCVDVQIISNSECEQAY-GSVASTDMCTRHAD-GKSVCGGDSGGPLVTHDNARLVGVI 232
             :..|.|||:|..::|.:|||.:| |.:.:...|....: ||..|.||||||:|:  |..|.|::
Human   166 ADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVS--NGELQGIV 228

  Fly   233 TFASVSC--HDGPSGYTRVSDYLEWIRD 258
            :: ...|  .:.|..||:|.:|::||:|
Human   229 SW-GYGCAQKNRPGVYTKVYNYVDWIKD 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18180	NP_648341.1	Tryp_SPc	36..259	CDD:238113	77/255 (30%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	77/255 (30%)