Protein Alignment CG18180 and PRSS1

DIOPT Version :10

• Sequence 1: NP_648341.1
• Gene: CG18180 / 39125
• FlyBaseID: FBgn0036024
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 81/277 - (29%)
• Similarity: 123/277 - (44%)
• Gaps: 60/277 - (21%)

  Fly     3 LFLLTLSAALALVAASPTGLNRTTLLSQGAEGRIVNGYPAPEGKAPYIVGLFIRTDGSNSG-AVG 66
            |.:||..|| ||.|....            :.:||.||...|...||.|.|       ||| ...
Human     4 LLILTFVAA-ALAAPFDD------------DDKIVGGYNCEENSVPYQVSL-------NSGYHFC 48

  Fly    67 AGTIIANDWILTAAHCL-------TGDY-VEIHYGSNWGWNGAYRQTVRRDNFISHPDWPSQG-G 122
            .|::|...|:::|.||.       .|:: :|:..|:        .|.:.....|.||.:..:. .
Human    49 GGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGN--------EQFINAAKIIRHPQYDRKTLN 105

  Fly   123 RDIGLIR-TPHVDFNGLINKIPLPSMNEQNDRYQDTWCVACGWG--GMDNGNLADWLQCVDVQII 184
            .||.||: :.....|..::.|.||:.....    .|.|:..|||  .....:..|.|||:|..::
Human   106 NDIMLIKLSSRAVINARVSTISLPTAPPAT----GTKCLISGWGNTASSGADYPDELQCLDAPVL 166

  Fly   185 SNSECEQAY-GSVASTDMCTRHAD-GKSVCGGDSGGPLVTHDNARLVGVITFASVSCHDG----- 242
            |.::||.:| |.:.|...|....: ||..|.||||||:|.  |.:|.||:::.     ||
Human   167 SQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVC--NGQLQGVVSWG-----DGCAQKN 224

  Fly   243 -PSGYTRVSDYLEWIRD 258
             |..||:|.:|::||::
Human   225 KPGVYTKVYNYVKWIKN 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18180	NP_648341.1	Tryp_SPc	36..259	CDD:238113	73/244 (30%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	71/241 (29%)