Protein Alignment CG18180 and KLK14

DIOPT Version :10

• Sequence 1: NP_648341.1
• Gene: CG18180 / 39125
• FlyBaseID: FBgn0036024
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_071329.3
• Gene: KLK14 / 43847
• HGNCID: 6362
• Length: 251
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 70/268 - (26%)
• Similarity: 117/268 - (43%)
• Gaps: 34/268 - (12%)

  Fly     3 LFLLTLSAALALVAASPTGLNRTTLLSQGAEGRIVNGYPAPEGKAPYIVGLFIRTDGSNSGAVGA 67
            :|||.  .||.::|.:.|       .||..|.:|:.|:.......|:...|..   |.....:..
Human     1 MFLLL--TALQVLAIAMT-------QSQEDENKIIGGHTCTRSSQPWQAALLA---GPRRRFLCG 53

  Fly    68 GTIIANDWILTAAHCLTGDYVEIHYGSN----WGWNGAYRQTVRRDNFISHPDWPSQ-GGRDIGL 127
            |.:::..|::||||| ....:::..|.:    |   .|.:|.:|....::||::.|: ...|:.|
Human    54 GALLSGQWVITAAHC-GRPILQVALGKHNLRRW---EATQQVLRVVRQVTHPNYNSRTHDNDLML 114

  Fly   128 IRTPHVDFNGLINKIPLPSMNEQNDRYQDTWCVACGWGGMDNGNLADW---LQCVDVQIISNSEC 189
            ::   :.....|.:...|....|......|.|...|||.: :..:|.:   ||||::.|..:..|
Human   115 LQ---LQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTI-SSPIARYPASLQCVNINISPDEVC 175

  Fly   190 EQAYGSVASTDMCTRHA--DGKSVCGGDSGGPLVTHDNARLVGVITFASVSC--HDGPSGYTRVS 250
            ::||....:..|.....  .||..|.||||||||.  ..:|.|::::....|  ...|..||.:.
Human   176 QKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVC--RGQLQGLVSWGMERCALPGYPGVYTNLC 238

  Fly   251 DYLEWIRD 258
            .|..||.:
Human   239 KYRSWIEE 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18180	NP_648341.1	Tryp_SPc	36..259	CDD:238113	60/235 (26%)
KLK14	NP_071329.3	Tryp_SPc	25..247	CDD:238113	60/235 (26%)