Protein Alignment CG18180 and TMPRSS11F

DIOPT Version :10

• Sequence 1: NP_648341.1
• Gene: CG18180 / 39125
• FlyBaseID: FBgn0036024
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_997290.2
• Gene: TMPRSS11F / 389208
• HGNCID: 29994
• Length: 438
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 77/263 - (29%)
• Similarity: 130/263 - (49%)
• Gaps: 26/263 - (9%)

  Fly    18 SPTGLNRTT----LLSQGAEGRIVNG-YPAPEGKAPYIVGLFIRTDGSNSGAVGAGTIIANDWIL 77
            |..|:..|:    |.:..:..|||.| ..|.||:.|:...|.:...|...||    ::|:|.|:|
Human   184 SRCGIRMTSSNMPLPASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGA----SLISNTWLL 244

  Fly    78 TAAHCLTGDYVEIHYGSNWGWN---GAYRQTVRRDNFISHPDWPSQ-GGRDIGLIR-TPHVDFNG 137
            |||||...:.....:.:.:|..   .|.::.||:  .|.|.::..: ...||.|:: :..|:|:.
Human   245 TAAHCFWKNKDPTQWIATFGATITPPAVKRNVRK--IILHENYHRETNENDIALVQLSTGVEFSN 307

  Fly   138 LINKIPLPSMNEQNDRYQDTWCVACGWGG-MDNGNLADWLQCVDVQIISNSEC--EQAY-GSVAS 198
            ::.::.||..:.:..  ..|.....|:|. :|:|.:.:.|:...|:.||...|  :..| |.:..
Human   308 IVQRVCLPDSSIKLP--PKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDGLITP 370

  Fly   199 TDMCTRHADGK-SVCGGDSGGPLV--THDNARLVGVITFA-SVSCHDGPSGYTRVSDYLEWIRDQ 259
            ..:|....:|| ..|.||||||||  .||...:||::::. |.:....|..||||:.|.:||..:
Human   371 GMLCAGFMEGKIDACKGDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWIASK 435

  Fly   260 TGI 262
            ||:
Human   436 TGM 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18180	NP_648341.1	Tryp_SPc	36..259	CDD:238113	70/236 (30%)
TMPRSS11F	NP_997290.2	SEA	59..158	CDD:460188
		Tryp_SPc	206..435	CDD:238113	70/236 (30%)