DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18180 and CG30187

DIOPT Version :9

Sequence 1:	NP_648341.1	Gene:	CG18180 / 39125	FlyBaseID:	FBgn0036024	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_001246475.2	Gene:	CG30187 / 246509	FlyBaseID:	FBgn0050187	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	242	Identity:	66/242 - (27%)
Similarity:	102/242 - (42%)	Gaps:	34/242 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVNGYPAPEGKAPYIVGLFIRTDGSNSGAVGAGTIIANDWILTAAHCLTG-DYVEIHYGSNWGW 98
            :|..|:.|....:.::..:..||.     .:..||:|...::||||||:.. |...:..
  Fly    35 KITGGHNAAFQNSVWMAAVHNRTH-----FICGGTLIHKRFVLTAAHCIVDQDVQSVSL------ 88

  Fly    99 NGAYRQT---VRRD--NFISHPDWPSQGG--RDIGLIR-TPHVDFNGLINK--IPLPSMNEQNDR 153
             |||.::   .|:|  ..:.|..:..:..  .||||:: :..|.||.||..  |.|......:.|
  Fly    89 -GAYNKSDPADRKDVITAVVHSSFDVRASYENDIGLLKLSSDVIFNALIRPICIVLNKSMANHMR 152

  Fly   154 YQDTWCVACGWGGMDNGNLADWLQCVDVQIISNSECEQAYGSVASTDMCTRHADGKSVCGGDSGG 218
            ...|: .|.|||.:.....:|.||.:.:..:...||........|.............|||||||
  Fly   153 NMRTF-KAFGWGTLRGNKTSDILQTIILNHLDREECYMELSVYPSEKQICAGVPSGDTCGGDSGG 216

  Fly   219 PLVTHD-------NARL-VGVITFASVSCHDGPSGYTRVSDYLEWIR 257
            || |:|       |..: .|:|:....|| ||...||.:..:.:||:
  Fly   217 PL-TNDVFIQGIGNREVQFGIISVGKTSC-DGQGVYTDLMSFADWIK 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18180	NP_648341.1	Tryp_SPc	35..256	CDD:214473	64/239 (27%)
CG18180	NP_648341.1	Tryp_SPc	36..259	CDD:238113	66/241 (27%)
CG30187	NP_001246475.2	Tryp_SPc	35..260	CDD:214473	64/239 (27%)
CG30187	NP_001246475.2	Trypsin	316..>384	CDD:355628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100