Protein Alignment CG18180 and Klk7

DIOPT Version :10

• Sequence 1: NP_648341.1
• Gene: CG18180 / 39125
• FlyBaseID: FBgn0036024
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_036002.1
• Gene: Klk7 / 23993
• MGIID: 1346336
• Length: 249
• Species: Mus musculus
• Alignment Length: 268
• Identity: 82/268 - (30%)
• Similarity: 130/268 - (48%)
• Gaps: 35/268 - (13%)

  Fly     1 MKLFLLTLSAALALVAASPTGLNRTTLLSQGAEGRIVNGYPAPEGKAPYIVGLFIRTDGSNSGAV 65
            |.::||:|...|..:|....|        ||.  ||::||...||..|:.|.| ::.:..:.|
Mouse     1 MGVWLLSLITVLLSLALETAG--------QGE--RIIDGYKCKEGSHPWQVAL-LKGNQLHCG-- 52

  Fly    66 GAGTIIANDWILTAAHCLTGDYVEIHYGSN-WGWNGAYRQTVRRDNFISHPDWPSQGG-RDIGLI 128
              |.::...|:||||||..|.| ::..||: .|...|  |.::......||.:.::.. .||.|:
Mouse    53 --GVLVDKYWVLTAAHCKMGQY-QVQLGSDKIGDQSA--QKIKATKSFRHPGYSTKTHVNDIMLV 112

  Fly   129 RTPH-VDFNGLINKIPLPSMNEQNDRYQDTWCVACGWGGMDNGNL---ADWLQCVDVQIISNSEC 189
            |... |..:..:..:.||...|.    ..|.|...|||...:.::   :| |.|.||::||:.||
Mouse   113 RLDEPVKMSSKVEAVQLPEHCEP----PGTSCTVSGWGTTTSPDVTFPSD-LMCSDVKLISSREC 172

  Fly   190 EQAYGS-VASTDMCTRHADGK-SVCGGDSGGPLVTHDNARLVGVITFASVSC--HDGPSGYTRVS 250
            ::.|.. :..|.:|....|.| :.|.||||||||.:|.  |.|::::.:..|  .:.|..||:|.
Mouse   173 KKVYKDLLGKTMLCAGIPDSKTNTCNGDSGGPLVCNDT--LQGLVSWGTYPCGQPNDPGVYTQVC 235

  Fly   251 DYLEWIRD 258
            .|..|:.:
Mouse   236 KYKRWVME 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18180	NP_648341.1	Tryp_SPc	36..259	CDD:238113	72/233 (31%)
Klk7	NP_036002.1	Tryp_SPc	25..241	CDD:214473	72/230 (31%)
		Serine protease. /evidence=ECO:0000250	26..246		72/233 (31%)