DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18180 and CG42694

DIOPT Version :9

Sequence 1:	NP_648341.1	Gene:	CG18180 / 39125	FlyBaseID:	FBgn0036024	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_001188994.1	Gene:	CG42694 / 10178792	FlyBaseID:	FBgn0261584	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	225	Identity:	49/225 - (21%)
Similarity:	86/225 - (38%)	Gaps:	65/225 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 AGTIIANDWILTAAHCLTGDYVEIHYGSNWGWNGAYRQTVRRDNFISHPDW--------PSQGG- 122
            :|::|:..::|:||.|     :::|        |.....:...|....|.|        ||..|
  Fly    59 SGSLISKQFVLSAAQC-----IDVH--------GKLFVQLGVSNATKSPHWYTVSNVVIPSHSGK 110

  Fly   123 ---RDIGLIR-TPHVDFNGLINKIPLPSMNEQNDRYQDTWCVACGWGGMD------NGNLADWL- 176
               |||||:: :..||:|..:..|                |:|.....:|      |...:.||
  Fly   111 RLQRDIGLLKLSQSVDYNDFVYPI----------------CIALNTNTLDMVKILQNFTTSAWLS 159

  Fly   177 -----QCVDVQIISNSECE-QAYGSVASTDMCTRHADGKSVCGGDSGG----PLVTHDN---ARL 228
                 |.:.:..:|...|: ...|:|...::|.......:.|..|||.    |::...|   ..|
  Fly   160 KNKNPQTIVLSQLSRDRCKLNLSGNVTPKEICAASLQRNNSCFIDSGSALTQPIIQGSNIVREML 224

  Fly   229 VGVITFASVS--CHDGPSGYTRVSDYLEWI 256
            .|:..:.:..  |.: |:.|..|::.:.||
  Fly   225 FGIRGYVNGRSWCSE-PAIYIDVAECVGWI 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18180	NP_648341.1	Tryp_SPc	35..256	CDD:214473	47/223 (21%)
CG18180	NP_648341.1	Tryp_SPc	36..259	CDD:238113	49/225 (22%)
CG42694	NP_001188994.1	Tryp_SPc	46..256	CDD:304450	49/225 (22%)
		Tryp_SPc	46..253	CDD:214473	47/223 (21%)
		Tryp_SPc	319..505	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435850
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030