DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18179 and C1S

DIOPT Version :9

Sequence 1:NP_648340.1 Gene:CG18179 / 39124 FlyBaseID:FBgn0036023 Length:268 Species:Drosophila melanogaster
Sequence 2:NP_001725.1 Gene:C1S / 716 HGNCID:1247 Length:688 Species:Homo sapiens


Alignment Length:256 Identity:68/256 - (26%)
Similarity:103/256 - (40%) Gaps:51/256 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 RIVNGYPAPEGKAPYIVGLLIRTDGSNSAAVGAGTIIASDWILTAAHCL-----TTDYVEIHYGS 98
            ||:.|..|.....|:.|..      .|..|.||  :|...|:|||||.:     .|.||    ||
Human   437 RIIGGSDADIKNFPWQVFF------DNPWAGGA--LINEYWVLTAAHVVEGNREPTMYV----GS 489

  Fly    99 NWGWNGAFRQS--VRRDNFISHPNWP----AEG----GRDIGLIRTPS-VGFTDLINKVALPSFS 152
            .........:|  :..::...||.|.    .||    ..||.|:|... |.....::.:.||..|
Human   490 TSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTS 554

  Fly   153 EESDRFVDTWCVACGWGGMDNGN-----------LADWLQCMDVQIISNSECEQSYGTVASTDM- 205
            .:.:.......:..|||..:..:           :|...:|.:|::...:...::|  |.:.:| 
Human   555 SDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAY--VFTPNMI 617

  Fly   206 CTRRTDGKSSCGGDSGGPLVTHD-NAR----LVGVITFGSVDCHSGPSG-YTRVTDYLGWI 260
            |.....|..||.|||||.....| |.:    ..|::::|. .|  |..| ||||.:|:.||
Human   618 CAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGP-QC--GTYGLYTRVKNYVDWI 675

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18179NP_648340.1 Tryp_SPc 39..260 CDD:214473 66/254 (26%)
Tryp_SPc 40..263 CDD:238113 67/255 (26%)
C1SNP_001725.1 CUB 18..129 CDD:238001
FXa_inhibition 143..171 CDD:405372
CUB 175..287 CDD:395345
CCP 294..355 CDD:153056
Sushi 359..421 CDD:395037
Tryp_SPc 438..678 CDD:238113 67/255 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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