DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18179 and zgc:100868

DIOPT Version :9

Sequence 1:	NP_648340.1	Gene:	CG18179 / 39124	FlyBaseID:	FBgn0036023	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	XP_005164187.1	Gene:	zgc:100868 / 554458	ZFINID:	ZDB-GENE-040801-33	Length:	654	Species:	Danio rerio

Alignment Length:	279	Identity:	87/279 - (31%)
Similarity:	136/279 - (48%)	Gaps:	34/279 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLFLLTLSVALAVVAASPGFNRTSLLPQVTISEGA--EGRIVNGYPAPEGKAPYIVGLLIRTDG 63
            ||:.::.:::.:|::        |....|:.:...|  ..|||.|..||.|..|:.|.|  :.||
Zfish     4 MKIHIVGVALTIALL--------TGCDAQLDVCGTAPLNSRIVGGQNAPVGAWPWQVSL--QRDG 58

  Fly    64 SNSAAVGAGTIIASDWILTAAHCL---TTDYVEIHYG-SNWGWNGAFRQSVRRDNFISHPNWPAE 124
            |:..   .|::|.:.||||||||.   :|..:.::.| .......::..|....|.|.|||:.::
Zfish    59 SHFC---GGSLINNQWILTAAHCFPNPSTTGLLVYLGLQKLASFESYSMSSAVSNIIKHPNYNSD 120

  Fly   125 -GGRDIGLIRTPS-VGFTDLINKVALPSFSEESDRFVDTWCVACGWGGMDNG-NLAD--WLQCMD 184
             ...||.|::..| |.|::.|..:.|.  :.:|..|..|.....|||....| :|..  .||.:.
Zfish   121 TEDNDITLLQLASTVSFSNYIRPICLA--ASDSTFFNGTLVWITGWGNTATGVSLPSPGTLQEVQ 183

  Fly   185 VQIISNSECEQSYGTVASTD--MCTRRTD-GKSSCGGDSGGPLVTHDNARLV--GVITFGSVDC- 243
            |.|:.|.:|...||....||  :|..... ||.||.||||||:|:...:..:  |:::||: .|
Zfish   184 VPIVGNRKCNCLYGVSKITDNMVCAGLLQGGKDSCQGDSGGPMVSKQGSVWIQSGIVSFGT-GCA 247

  Fly   244 -HSGPSGYTRVTDYLGWIR 261
             .:.|..||||:.|..||:
Zfish   248 QPNFPGVYTRVSKYQSWIQ 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18179	NP_648340.1	Tryp_SPc	39..260	CDD:214473	79/236 (33%)
CG18179	NP_648340.1	Tryp_SPc	40..263	CDD:238113	80/238 (34%)
zgc:100868	XP_005164187.1	Tryp_SPc	36..265	CDD:214473	79/236 (33%)
		Tryp_SPc	37..267	CDD:238113	80/238 (34%)
		Tryp_SPc	331..509	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910