DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18179 and prss27

DIOPT Version :9

Sequence 1:	NP_648340.1	Gene:	CG18179 / 39124	FlyBaseID:	FBgn0036023	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	297	Identity:	88/297 - (29%)
Similarity:	128/297 - (43%)	Gaps:	70/297 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 AVVAASPGFNRTSLLPQVTISEGA--------EGRIVNGYPAPEGKAPYIVGLLIRTDGSNSAAV 69
            |::..:||.        :.|:.||        ..||:.|..|.||:.|:.|.  .|.:|.:..
Frog     7 ALLLLTPGL--------LGITPGATDCGIPLVSSRIMGGQSAQEGQWPWQVS--FRNNGGHFC-- 59

  Fly    70 GAGTIIASDWILTAAHCLTTDYVEIHYGSNWGWNGAFRQSVRRDNFISHP-----NWPA---EG- 125
             .||:|:..::::||||..:   .....|.....||:.......|.::.|     |:|:   ||
Frog    60 -GGTLISKQYVISAAHCFPS---SSSASSVTAVLGAYMIDQPDGNQVAIPVQSATNYPSYVNEGD 120

  Fly   126 GRDIGLIRTPS-VGFTDLINKVALPSFSEESDRFVDTWCVACGWGGMDNGNLAD--------WLQ 181
            ..||.|::..| |.||:.|..|.||:.:......:..|  ..||     ||:|.        .||
Frog   121 SGDISLVQLASPVTFTNYILPVCLPADTVTFPTGLQCW--VTGW-----GNIASDVSLVSPMTLQ 178

  Fly   182 CMDVQIISNSECE------QSYGT----VASTDMCTRRTD-GKSSCGGDSGGPLVTHDNAR--LV 233
            .:.|.:|..:||.      .||||    |.|..:|....: ||.||.||||||||...:.:  |.
Frog   179 EVAVPLIDANECNALYQTPNSYGTSSISVHSDMICAGFINGGKDSCQGDSGGPLVCSSSGQWFLA 243

  Fly   234 GVITFGSVDCHSG--PSGYTRVTDYLGWIRDNTGISY 268
            ||::||. .|...  |..||.:..|..||     :||
Frog   244 GVVSFGE-GCGQAYRPGVYTLMPSYTDWI-----VSY 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18179	NP_648340.1	Tryp_SPc	39..260	CDD:214473	78/253 (31%)
CG18179	NP_648340.1	Tryp_SPc	40..263	CDD:238113	79/255 (31%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113	77/252 (31%)
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910