DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18179 and spirit

DIOPT Version :9

Sequence 1:	NP_648340.1	Gene:	CG18179 / 39124	FlyBaseID:	FBgn0036023	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_001162707.1	Gene:	spirit / 31797	FlyBaseID:	FBgn0030051	Length:	393	Species:	Drosophila melanogaster

Alignment Length:	250	Identity:	69/250 - (27%)
Similarity:	108/250 - (43%)	Gaps:	49/250 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 IVNGYPAPEGKAPYIVGLLIRTDGSNSAAVG-AGTIIASDWILTAAHC------------LTTDY 91
            :|.|.|....:.|::..|..|::........ .|.:||::::||||||            |..|.
  Fly   132 VVGGMPTRPREFPFMAALGWRSNFDQRIYYRCGGALIANNFVLTAAHCADLGGEPPSQVRLGGDN 196

  Fly    92 VEIHYGSNWGWNGAFRQSVRRDNFISHPNWPAEGG-RDIGLIRTPSVGFTDLINKVALPSFSEES 155
            :.:..|.:        .|:||  .|.||::.|... .||.|:...:....:|     .|:.....
  Fly   197 LTLTEGED--------ISIRR--VIIHPDYSASTAYNDIALLELETAAKPEL-----KPTCIWTQ 246

  Fly   156 DRFVDTWCVACGWG-----GMDNGNLADWLQCMDVQIISNSECEQSYGT------VASTDMCTRR 209
            ....:|...|.|:|     |:.:..|..    :.::.:||.||:..|..      |..|.||...
  Fly   247 KEVTNTLVTAIGYGQTSFAGLSSAQLLK----VPLKSVSNEECQHHYQKDQLAQGVLGTQMCAGD 307

  Fly   210 TDG-KSSCGGDSGGPLVTHDN--ARLVGVITFGSVDCHSG-PSGYTRVTDYLGWI 260
            ..| :.:|.|||||||:..|.  ..:||:.:.|. .|.|| ||.||||:.::.||
  Fly   308 ITGERDTCQGDSGGPLLMQDGLLGYVVGITSLGQ-GCASGPPSVYTRVSSFVDWI 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18179	NP_648340.1	Tryp_SPc	39..260	CDD:214473	67/248 (27%)
CG18179	NP_648340.1	Tryp_SPc	40..263	CDD:238113	68/249 (27%)
spirit	NP_001162707.1	CLIP	51..98	CDD:197829
		Tryp_SPc	132..364	CDD:238113	68/249 (27%)
		Tryp_SPc	132..361	CDD:214473	67/248 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436987
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940