DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8329 and C1s1

DIOPT Version :9

Sequence 1:	NP_648339.1	Gene:	CG8329 / 39123	FlyBaseID:	FBgn0036022	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_001091086.1	Gene:	C1s1 / 50908	MGIID:	1355312	Length:	694	Species:	Mus musculus

Alignment Length:	256	Identity:	68/256 - (26%)
Similarity:	94/256 - (36%)	Gaps:	44/256 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 IVNGYPAYEGKAPYAVGLRMNNGAVGGGSVIGNNWVLTAAHCLTTDSVTIHYGSNRAWNGQLQHT 99
            |..|.||.....|:.|   ..|.....|::|...|||||||.|...|..:.|....:....|...
Mouse   444 IFGGQPAKIENFPWQV---FFNHPRASGALINEYWVLTAAHVLEKISDPLMYVGTMSVRTTLLEN 505

  Fly   100 VNK---NNFFRHPGY-----PNSA---GHDIGLI--RTPYVSFTNLINKVSLPKFSQKGERFENW 151
            ..:   ...|.||.:     ||:.   .:||.|:  :.| |.....::.:.||..|.:.......
Mouse   506 AQRLYSKRVFIHPSWKKEDDPNTRTNFDNDIALVQLKDP-VKMGPKVSPICLPGTSSEYNVSPGD 569

  Fly   152 WCVACGWGGMANGGLADWLQCMDVQVISNGEC---------ARSYGSVASTDMCTRATDGKSVCG 207
            ..:..|||..........|:...|.|.|...|         .|....|.:.:|......|...|.
Mouse   570 MGLISGWGSTEKKVFVINLRGAKVPVTSLETCKQVKEENPTVRPEDYVFTDNMICAGEKGVDSCH 634

  Fly   208 GDSGGALVTHDNPIQVGVIT--------FASIGCKSGPSG-YTRVSDHLDWI----REKSG 255
            ||||||..     .||..:|        ..|.|.:.|..| ||:|.:::|||    :|.||
Mouse   635 GDSGGAFA-----FQVPNVTVPKFYVAGLVSWGKRCGTYGVYTKVKNYVDWILKTMQENSG 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8329	NP_648339.1	Tryp_SPc	35..253	CDD:238113	65/252 (26%)
CG8329	NP_648339.1	Tryp_SPc	35..250	CDD:214473	63/245 (26%)
C1s1	NP_001091086.1	CUB	24..135	CDD:238001
		FXa_inhibition	149..177	CDD:373209
		CUB	181..293	CDD:366096
		CCP	307..361	CDD:153056
		CCP	365..428	CDD:153056
		Tryp_SPc	443..681	CDD:214473	63/245 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000