DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8329 and C1s2

DIOPT Version :9

Sequence 1:	NP_648339.1	Gene:	CG8329 / 39123	FlyBaseID:	FBgn0036022	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_776289.2	Gene:	C1s2 / 317677	MGIID:	3644269	Length:	694	Species:	Mus musculus

Alignment Length:	265	Identity:	76/265 - (28%)
Similarity:	100/265 - (37%)	Gaps:	62/265 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 IVNGYPAYEGKAPYAVGLRMNNGAVGGGSVIGNNWVLTAAHCLTTDSVTIHYGSNRAW------N 93
            |..|.||.....|:.|   ..|....||::|...|||||||.:..:|....|....|.      |
Mouse   444 IFGGQPAKIENFPWQV---FFNHPTAGGALINEYWVLTAAHVVEKNSDPSMYAGITALRLADLEN 505

  Fly    94 GQLQHTVNKNNFFRHPGYPNSAGHDIGLIRTPYVSFTNLINKVSL-------PKFSQ---KGERF 148
            .|..:|   .....|||:...  .|:    .|..:|.|.|..|.|       ||||.   .|...
Mouse   506 AQRLYT---KRVIIHPGWKED--DDL----NPRTNFDNDIALVQLKDPVKMGPKFSPICLPGTSS 561

  Fly   149 ENWWCVACGWGGMANGGLADW-----------LQCMDVQVISNGEC---------ARSYGSVAST 193
            |  :.::.|..|:.:|    |           |:...|.|.|...|         ||....|.:.
Mouse   562 E--YNLSPGDMGLISG----WGRTEKRLHVINLRGAKVPVTSLETCKQVKEENPTARPEDYVITD 620

  Fly   194 DMCTRATDGKSVCGGDSGGAL---VTHDNPIQVGVITFASIGCKSGPSG-YTRVSDHLDWI---- 250
            :|......|...|.||||||.   |.:....:..|....|.|.|.|..| ||:|.:::|||
Mouse   621 NMICAGEKGVDSCKGDSGGAFAFQVPNVKAPKFYVAGLVSWGKKCGAYGVYTKVKNYVDWILKTM 685

  Fly   251 REKSG 255
            :|.||
Mouse   686 QENSG 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8329	NP_648339.1	Tryp_SPc	35..253	CDD:238113	73/261 (28%)
CG8329	NP_648339.1	Tryp_SPc	35..250	CDD:214473	71/254 (28%)
C1s2	NP_776289.2	CUB	24..135	CDD:238001
		FXa_inhibition	149..177	CDD:291342
		CUB	181..293	CDD:278839
		CCP	300..361	CDD:153056
		CCP	365..428	CDD:153056
		Tryp_SPc	443..681	CDD:214473	71/254 (28%)
		Tryp_SPc	444..684	CDD:238113	73/257 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000