DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8336 and CPR1

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_010439.1	Gene:	CPR1 / 851733	SGDID:	S000002562	Length:	162	Species:	Saccharomyces cerevisiae

Alignment Length:	167	Identity:	75/167 - (44%)
Similarity:	103/167 - (61%)	Gaps:	8/167 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIKRVFVVQ 81
            ||.|:....:..||::.:|..|:|||||||||||||||.|.|       |.|:.||::...|::|
Yeast     4 VYFDVEADGQPIGRVVFKLYNDIVPKTAENFRALCTGEKGFG-------YAGSPFHRVIPDFMLQ 61

  Fly    82 SGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCENLNGTNV 146
            .||....:|:.|:||||..|.||||:..|:..|::||||.| ||:|.|||||:...|..|:|.:|
Yeast    62 GGDFTAGNGTGGKSIYGGKFPDENFKKHHDRPGLLSMANAG-PNTNGSQFFITTVPCPWLDGKHV 125

  Fly   147 VVGRVLRGLGIVAEMEQNCTDEGDPTAPIVIRDCGEI 183
            |.|.|:.|..||.::|...:..|...|.||:...||:
Yeast   126 VFGEVVDGYDIVKKVESLGSPSGATKARIVVAKSGEL 162

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	73/163 (45%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
CPR1	NP_010439.1	cyclophilin_ABH_like	2..160	CDD:238907	73/163 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343452
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740