DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8336 and Ppil6

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_082706.1	Gene:	Ppil6 / 73075	MGIID:	1920325	Length:	313	Species:	Mus musculus

Alignment Length:	177	Identity:	70/177 - (39%)
Similarity:	99/177 - (55%)	Gaps:	3/177 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KLLRAVKSTNPLVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGT 69
            |.|:..|  :..|||||.|.....||:|.||..|..|:|..||:.||||..|....|..||||.:
Mouse   136 KFLKDTK--HDFVYLDICIDLSPIGRLIFELYCDACPRTCTNFQVLCTGTSGFSERGTKLHYKDS 198

  Fly    70 KFHKIKRVFVVQSGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFIS 134
            .||::.:...:|.||:|:..|..|||||||.|:||||.:.||:.||:.|.|.|. ::|.|||:|:
Mouse   199 IFHRVVQNGWIQGGDIVQGRGDDGESIYGPTFEDENFSIPHNKRGVLGMVNKGH-HTNGSQFYIT 262

  Fly   135 AAGCENLNGTNVVVGRVLRGLGIVAEMEQNCTDEGDPTAPIVIRDCG 181
            ......|:...|..|:::.|..::.::|...|:...|.....|.|.|
Mouse   263 LQAAPYLDKKYVAFGQLIEGTHVLKQLELVPTENERPLLLCSIADSG 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	66/165 (40%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
Ppil6	NP_082706.1	cyclophilin	146..309	CDD:294131	66/163 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836077
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740