DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8336 and Ppih

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_001103600.1	Gene:	Ppih / 66101	MGIID:	106499	Length:	188	Species:	Mus musculus

Alignment Length:	149	Identity:	73/149 - (48%)
Similarity:	104/149 - (69%)	Gaps:	3/149 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 NPLVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIKRVF 78
            ||:|:.|:|||.::.|||.|||..|||||||||||..||||  ....|.|:.|||:.||::.:.|
Mouse    10 NPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGE--FRKDGVPIGYKGSTFHRVIKDF 72

  Fly    79 VVQSGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCENLNG 143
            ::|.||.|..||:...|||...|.||||:|.|:..|::||||.| |::|..||||:.:.|:.|:|
Mouse    73 MIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSG-PSTNGCQFFITCSKCDWLDG 136

  Fly   144 TNVVVGRVLRGLGIVAEME 162
            .:||.|:::.||.::.::|
Mouse   137 KHVVFGKIIDGLLVMRKIE 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	72/148 (49%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
Ppih	NP_001103600.1	cyclophilin_ABH_like	11..155	CDD:238907	71/146 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910