DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8336 and PPIAL4C

DIOPT Version :9

Sequence 1:NP_001261636.1 Gene:CG8336 / 39121 FlyBaseID:FBgn0036020 Length:383 Species:Drosophila melanogaster
Sequence 2:NP_001129261.2 Gene:PPIAL4C / 653598 HGNCID:33995 Length:164 Species:Homo sapiens


Alignment Length:169 Identity:74/169 - (43%)
Similarity:98/169 - (57%) Gaps:8/169 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 NPLVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIKRVF 78
            |.:|:.||::..:..||:.|:|..|.:||||||||||.|||       |...|||:.||:|...|
Human     3 NSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGE-------KGFRYKGSCFHRIIPGF 60

  Fly    79 VVQSGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCENLNG 143
            :.|.||..:.:|:..:||||..|||||....|...|::||||.| ||:|.|||||..|..|.|:|
Human    61 MCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAG-PNTNGSQFFICTAKTEWLDG 124

  Fly   144 TNVVVGRVLRGLGIVAEMEQNCTDEGDPTAPIVIRDCGE 182
            .:|..|:|...:.||..||.........:..|.|.|||:
Human   125 KHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQ 163

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8336NP_001261636.1 cyclophilin 15..181 CDD:294131 71/165 (43%)
TPR repeat 285..315 CDD:276809
TPR_19 300..369 CDD:291240
TPR_1 320..353 CDD:278916
TPR repeat 320..346 CDD:276809
PPIAL4CNP_001129261.2 cyclophilin 4..162 CDD:320812 71/165 (43%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165146004
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0652
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1403619at2759
OrthoFinder 1 1.000 - - FOG0000032
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
54.750

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