DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8336 and RANBP2

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	XP_005264059.1	Gene:	RANBP2 / 5903	HGNCID:	9848	Length:	3258	Species:	Homo sapiens

Alignment Length:	173	Identity:	77/173 - (44%)
Similarity:	111/173 - (64%)	Gaps:	8/173 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 KSTNPLVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIK 75
            |.|||:|:.|:....|..||:.:||..::||:||||||||||||.|.|       :|.:.||::.
Human  3094 KETNPVVFFDVCADGEPLGRITMELFSNIVPRTAENFRALCTGEKGFG-------FKNSIFHRVI 3151

  Fly    76 RVFVVQSGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCEN 140
            ..||.|.||:.|:||:.|:||||..|:||||::.|...|::||||.|: |:|||||.|:....|:
Human  3152 PDFVCQGGDITKHDGTGGQSIYGDKFEDENFDVKHTGPGLLSMANQGQ-NTNNSQFVITLKKAEH 3215

  Fly   141 LNGTNVVVGRVLRGLGIVAEMEQNCTDEGDPTAPIVIRDCGEI 183
            |:..:||.|.|..|:..|.::|...:.:|.....|.|.:||:|
Human  3216 LDFKHVVFGFVKDGMDTVKKIESFGSPKGSVCRRITITECGQI 3258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	71/165 (43%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
RANBP2	XP_005264059.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810