DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8336 and Ppie

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_062362.1	Gene:	Ppie / 56031	MGIID:	1917118	Length:	301	Species:	Mus musculus

Alignment Length:	170	Identity:	81/170 - (47%)
Similarity:	110/170 - (64%)	Gaps:	8/170 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 TNPLVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIKRV 77
            :||.||:||.||.:.|||:.:.||.||||.||||||.|||.|.|.|       :||:.||:|...
Mouse   138 SNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEKGFG-------FKGSSFHRIIPQ 195

  Fly    78 FVVQSGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCENLN 142
            |:.|.||...::|:.|:||||..||||||.|.|...|::||||.| ||:|.||||::....:.|:
Mouse   196 FMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGPGLLSMANSG-PNTNGSQFFLTCDKTDWLD 259

  Fly   143 GTNVVVGRVLRGLGIVAEMEQNCTDEGDPTAPIVIRDCGE 182
            |.:||.|.|..||.::.::|...:.:|.|...::|.||||
Mouse   260 GKHVVFGEVTEGLDVLRQIEAQGSKDGKPKQKVMIADCGE 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	77/165 (47%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
Ppie	NP_062362.1	RRM	<5..194	CDD:223796	34/62 (55%)
		RRM_PPIE	8..80	CDD:240793
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	110..141		1/2 (50%)
		cyclophilin_ABH_like	140..298	CDD:238907	77/165 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836079
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740