DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cyp40 and ppie

DIOPT Version :10

Sequence 1:NP_648338.1 Gene:Cyp40 / 39121 FlyBaseID:FBgn0036020 Length:383 Species:Drosophila melanogaster
Sequence 2:NP_001017678.1 Gene:ppie / 550373 ZFINID:ZDB-GENE-050417-167 Length:302 Species:Danio rerio


Alignment Length:170 Identity:81/170 - (47%)
Similarity:107/170 - (62%) Gaps:8/170 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 TNPLVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIKRV 77
            |||.||:||.||.:.|||:...||.||||.||||||.|||.|.|.|       :||:.||:|...
Zfish   139 TNPQVYMDIKIGNKPAGRLRFLLRADVVPMTAENFRCLCTHEKGFG-------FKGSSFHRIIPQ 196

  Fly    78 FVVQSGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCENLN 142
            |:.|.||...::|:.|:||||..|:||||.|.|...|.:||||.| ||:|.|||||:....:.|:
Zfish   197 FMCQGGDFTNHNGTGGKSIYGRKFEDENFVLKHTHAGQLSMANSG-PNTNGSQFFITVDKTDWLD 260

  Fly   143 GTNVVVGRVLRGLGIVAEMEQNCTDEGDPTAPIVIRDCGE 182
            |.:||.|.:..|:.::..||...|.:|.|...::|.:|||
Zfish   261 GKHVVFGELTEGMDVLRAMEAQGTKDGKPKQKVIISNCGE 300

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cyp40NP_648338.1 cyclophilin 15..181 CDD:469651 76/165 (46%)
TPR 231..>370 CDD:440225
TPR repeat 285..315 CDD:276809
TPR repeat 320..346 CDD:276809
ppieNP_001017678.1 RRM_PPIE 8..82 CDD:409783
cyclophilin_ABH_like 141..299 CDD:238907 76/165 (46%)
Blue background indicates that the domain is not in the aligned region.

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