DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8336 and ppib

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_001017063.1	Gene:	ppib / 549817	XenbaseID:	XB-GENE-855964	Length:	208	Species:	Xenopus tropicalis

Alignment Length:	191	Identity:	86/191 - (45%)
Similarity:	115/191 - (60%)	Gaps:	12/191 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EERKLLRAVKSTNPLVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHY 66
            :|:|  :..|.|:. ||.||.||.||.||::|.|....||||.|||..|.|||.|.|       |
Frog    26 DEKK--KGPKVTHK-VYFDIKIGDEDVGRVVIGLFGKTVPKTVENFVTLATGEKGFG-------Y 80

  Fly    67 KGTKFHKIKRVFVVQSGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQF 131
            ||:|||::.:.|::|.||..:.||:.|:||||..|.||||:|.|.....|||||.|| ::|.|||
Frog    81 KGSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGDRFPDENFKLRHYGPNWVSMANAGK-DTNGSQF 144

  Fly   132 FISAAGCENLNGTNVVVGRVLRGLGIVAEMEQNCTDEGD-PTAPIVIRDCGEIAHNEDWGI 191
            ||:......|:|.:||.|::|.|..:|.::|...||..| |...:||.|||.|...:.:.|
Frog   145 FITTVKTPWLDGKHVVFGKILEGKDVVEKIESTKTDGRDKPLKDVVIADCGTIEVEKPFAI 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	78/166 (47%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
ppib	NP_001017063.1	cyclophilin_ABH_like	36..195	CDD:238907	78/167 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010