DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8336 and ppil1

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_001005007.1	Gene:	ppil1 / 448493	XenbaseID:	XB-GENE-963801	Length:	166	Species:	Xenopus tropicalis

Alignment Length:	157	Identity:	58/157 - (36%)
Similarity:	83/157 - (52%)	Gaps:	18/157 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 PLVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIKRVFV 79
            |.|.|:.|:     |.:.:||.....|.|.:||          ..|.:..:|.|||||:|.:.|:
Frog    12 PHVLLETSM-----GTITVELYWLHAPMTCKNF----------AELARRGYYNGTKFHRIIKDFM 61

  Fly    80 VQSGDVVKNDGSSGESIYGPVFDDE-NFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCENLNG 143
            ||.||.. ..|..|.||||..|:|| :.:|.....|:::|||.| |:||.||||::.|..:.|:|
Frog    62 VQGGDPT-GTGRGGASIYGKQFEDEIHPDLKFTGAGILAMANAG-PDSNGSQFFLTLAPTQWLDG 124

  Fly   144 TNVVVGRVLRGLGIVAEMEQNCTDEGD 170
            .:.:.|||..|||.:..:....||..|
Frog   125 KHSIFGRVSHGLGTLNRLGMVETDSQD 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	58/157 (37%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
ppil1	NP_001005007.1	cyclophilin_SpCYP2_like	15..161	CDD:238903	56/154 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000