DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8336 and T22F3.12

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_001041170.1	Gene:	T22F3.12 / 4363086	WormBaseID:	WBGene00044705	Length:	174	Species:	Caenorhabditis elegans

Alignment Length:	179	Identity:	63/179 - (35%)
Similarity:	95/179 - (53%)	Gaps:	26/179 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIKRVFVVQ 81
            |::||:......|:::.||..:..|||.|||..||||..|.|       ||...|:::...|...
Worm     5 VFMDITADGAPLGKLVFELNTEKCPKTCENFVKLCTGPPGFG-------YKNCVFYRVIPTFCAC 62

  Fly    82 SGDV----VKNDGSSGESIYG-PVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCENL 141
            |||.    .:.||  |:|.:| ..|||||||:.|:::|::.|.|||..|:|:|:|:::......:
Worm    63 SGDFETQNARRDG--GKSTFGTKYFDDENFEILHDKKGILGMDNYGWENTNSSRFYVTFRETPWM 125

  Fly   142 NGTNVVVGRVLRG---------LGIVAEMEQNCTDEGDPTAPIVIRDCG 181
            |..:|..|.::.|         |||   :|.|...:|...|.|||.:||
Worm   126 NRFHVAFGELVEGFDVLDAIENLGI---LEGNGPQQGRTKANIVIANCG 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	61/177 (34%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
T22F3.12	NP_001041170.1	cyclophilin	4..171	CDD:294131	61/177 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11071
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010