DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8336 and ppid

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_988984.1	Gene:	ppid / 394581	XenbaseID:	XB-GENE-855598	Length:	370	Species:	Xenopus tropicalis

Alignment Length:	376	Identity:	155/376 - (41%)
Similarity:	229/376 - (60%)	Gaps:	24/376 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 TNPLVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIG-TLGKPLHYKGTKFHKIKR 76
            :||.|:||:.||.|..||:::||..|||||||||||||.|||.||| :.|||||:||..||:|.:
Frog    14 SNPKVFLDVEIGGERVGRIVLELFADVVPKTAENFRALSTGEKGIGQSTGKPLHFKGCPFHRIIK 78

  Fly    77 VFVVQSGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCENL 141
            .|::|.||....:|:.||||||..|:||||...|::||::||||.| ||:|.|||||:.....:|
Frog    79 KFMIQCGDFSNQNGTGGESIYGEKFEDENFHYKHDKEGLLSMANAG-PNTNGSQFFITTVPTAHL 142

  Fly   142 NGTNVVVGRVLRGLGIVAEMEQNCTDEGDPTAPIVIRDCGEIAHNEDWGIECNDETTDKLPAYPQ 206
            :|.:||.|:||:|.|||..:|.....:..|....||.:|||:...::|.....|.:.|..|.:|:
Frog   143 DGKHVVFGQVLKGYGIVKMLENVEVKDEKPAKMCVIAECGELNDRDEWISSPADGSGDTHPDFPE 207

  Fly   207 DWPRKLDKFTGDGAVELLTGIRQS----GNHFYQLGRYHEARAKYRKANRYYHYLSRQFGWQQLN 267
            |...:|:.      ||.:|.|.::    ||:|::...:..|..||.||.||            :.
Frog   208 DSDVELND------VERITSIAENVKNIGNNFFKSQNWEMATKKYNKALRY------------VE 254

  Fly   268 PLKKHLVDEDLLKVDGFSVVNNINAAAVDLKVGNYTSAREVCNEAIRLDPKCSKAFYRRAQAQRG 332
            ..|....|:::.|::..:|..|:|.||..|||.::.:|.:.||||:.:||..:||.|||||..:|
Frog   255 SCKDVTGDDNISKLNPIAVSCNLNIAACKLKVSDFRAAIDSCNEALEIDPSHTKALYRRAQGWQG 319

  Fly   333 LRNYEEAINDLKTAHNLLPENKQILNELNSTKQLLAQYNRQQRNALKNLFA 383
            |::||:|:.|||.||.|.|::|.:..|:...||.:.:...:::.....:||
Frog   320 LKDYEQALEDLKKAHELSPDDKAVSGEILRVKQRIKEQKEKEKAVYAKMFA 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	87/166 (52%)
		TPR repeat	285..315	CDD:276809	13/29 (45%)
		TPR_19	300..369	CDD:291240	30/68 (44%)
		TPR_1	320..353	CDD:278916	19/32 (59%)
		TPR repeat	320..346	CDD:276809	15/25 (60%)
ppid	NP_988984.1	cyclophilin_ABH_like	16..182	CDD:238907	87/166 (52%)
		3a0801s09	192..>362	CDD:273380	61/187 (33%)
		TPR repeat	223..267	CDD:276809	12/55 (22%)
		TPR repeat	272..302	CDD:276809	13/29 (45%)
		TPR repeat	307..335	CDD:276809	16/27 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31283
Inparanoid	1	1.050	256	1.000	Inparanoid score	I3077
OMA	1	1.010	-	-		QHG53622
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	1	1.000	-	-		oto105407
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3406
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.980