DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8336 and ppia

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_988875.1	Gene:	ppia / 394470	XenbaseID:	XB-GENE-5778000	Length:	164	Species:	Xenopus tropicalis

Alignment Length:	169	Identity:	81/169 - (47%)
Similarity:	107/169 - (63%)	Gaps:	8/169 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 PLVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIKRVFV 79
            |.|:.||::.....||:|:|||.|||||||||||||||.|.|.|       ||.:.||:|...|:
Frog     4 PRVFFDIAVDGCPMGRIIMELRSDVVPKTAENFRALCTNEKGFG-------YKNSGFHRIIPEFM 61

  Fly    80 VQSGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCENLNGT 144
            .|.||...::|:.|:||||..|.||||:|.|...|::||||.| .|:|.|||||..|....|:|.
Frog    62 CQGGDFTNHNGTGGKSIYGNKFADENFQLRHTGPGILSMANAG-ANTNGSQFFICTAKTSWLDGK 125

  Fly   145 NVVVGRVLRGLGIVAEMEQNCTDEGDPTAPIVIRDCGEI 183
            :||.|.|:.|:.:|..||:..:..|.|...|||.:||::
Frog   126 HVVFGTVIDGMDVVRNMEKLGSQSGKPAKKIVIANCGQL 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	79/165 (48%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
ppia	NP_988875.1	cyclophilin_ABH_like	4..162	CDD:238907	79/165 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11071
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020