DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8336 and Ppial4g

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	XP_341364.2	Gene:	Ppial4g / 361080	RGDID:	1559682	Length:	195	Species:	Rattus norvegicus

Alignment Length:	194	Identity:	78/194 - (40%)
Similarity:	111/194 - (57%)	Gaps:	12/194 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 NPLVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIKRVF 78
            |..::.:|:...|..||:.:||..|.||:||||||:|.|||.|.|       |||:.||:|...|
  Rat     3 NLTMFFNITADGEPLGRVSLELFADKVPRTAENFRSLTTGEKGFG-------YKGSSFHRIIPGF 60

  Fly    79 VVQSGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCENLNG 143
            :.|.|.|..::|:.|:||||..|::::|.|.|...|::||||.| ||:|.|||||..|..|.|:|
  Rat    61 MCQGGKVTCHNGTGGKSIYGEKFENDSFILKHTGPGILSMANAG-PNTNGSQFFICTAKTERLDG 124

  Fly   144 TNVVVGRVLRGLGIVAEMEQNCTDEGDPTAPIVIRDCGEIAHNEDWGIECNDETTDKLPAYPQD 207
            ..||.|:...|..||..||...:..|..:..|.|.|||::..:    :.|...|...:|:..|:
  Rat   125 KCVVFGKGRGGTNIVEAMEHFGSRNGKTSKKITISDCGQLLVS----LICGHFTHQTIPSVAQE 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	71/165 (43%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
Ppial4g	XP_341364.2	cyclophilin	7..162	CDD:294131	71/162 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339745
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840